Efficacy and Safety of Probiotics for Anxiety Depression

Summary

This randomized, double-blind, placebo-controlled study will enroll 60 individuals with mild-to-moderate anxiety depression. Following a 3-month intervention and a 1-month follow-up period, the study aims to: 1) evaluate the efficacy of probiotics by comparing anxiety, depression, and sleep scores to baseline; and 2) investigate the safety and underlying mechanisms by analyzing changes in serum biomarkers, gut microbiota, and related metabolites.

Timeline

Start

2026-06-15

Primary completion

2026-12-30

Completion

2027-02-28

Drugs

Indications