Circadian Effects of Escitalopram

Summary

The goal of the study is to obtain preliminary data that will test whether the antidepressant medication escitalopram resets the body clock: a collection of nerve cells in the brain that control the timing of many body processes. The study will also test whether the improvement in depression symptoms with escitalopram correlates with the degree to which the timing of the body clock is properly aligned with the timing of sleep.

Timeline

Start

2008-05

Primary completion

2011-12

Completion

2011-12

Outcome

Missed primary endpoint

registry analysis (other test); Study Drug; p = 0.2; t-test, 2 sided; note: A priori threshold for significance was p = 0.05. NCT01214044 ↗

Drugs

Indications