drugset / Trial / NCT04747314
Treating Negative Affect in Low Back Pain Patients
Phase 2/3
Completed
308 enrolled
Ajay Wasan, MD, Msc
Massachusetts General Hospital · collabMayo Clinic · collabNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · collabNational Institutes of Health (NIH) · collab
RandomizedSequentialDouble-blindTreatment
Summary
This study will examine how the use of antidepressant, physical therapy, and combination of both affects pain, function, and depression outcomes in chronic low back pain patients.
Timeline
- Start
- 2021-03-31
- Primary completion
- 2024-11-04
- Completion
- 2024-12-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aripiprazole | Other / unclassified | — | — |
| Subject | Bupropion | Small molecule | — | — |
| Subject | Duloxetine | Small molecule | — | — |
| Subject | Escitalopram | Small molecule | — | — |
| Subject | Mirtazapine | Other / unclassified | — | — |
| Subject | Sertraline | Small molecule | — | — |
| Subject | Venlafaxine | Small molecule | — | — |