drugset / Trial / NCT03346239
Effect of Attention Training or SSRIs on Symptoms and Neural Activation in Social Anxiety
Completed
105 enrolled
Tel Aviv University
Sheba Medical Center · collabTel-Aviv Sourasky Medical Center · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine the clinical efficacy and neuro-cognitive mechanisms of Gaze-Contingent Usic Reward Therapy for social anxiety disorder, compared with treatment with SSRIs or waitlist control.
Timeline
- Start
- 2018-07-20
- Primary completion
- 2021-12-01
- Completion
- 2021-12-01
Publications
- Azriel O, Arad G, Tik N, Weiser M, Bloch M, Garber E, Lazarov A, Pine DS, Tavor I, Bar-Haim Y. Neural activation changes following attention bias modification treatment or a selective serotonin reuptake inhibitor for social anxiety disorder. Psychol Med. 2024 Sep;54(12):3366-3378. doi: 10.1017/S0033291724001521. Epub 2024 Sep 10.
- Arad G, Azriel O, Pine DS, Lazarov A, Sol O, Weiser M, Garber E, Bloch M, Bar-Haim Y. Attention Bias Modification Treatment Versus a Selective Serotonin Reuptake Inhibitor Or Waiting List Control for Social Anxiety Disorder: A Randomized Clinical Trial. Am J Psychiatry. 2023 May 1;180(5):357-366. doi: 10.1176/appi.ajp.20220533. Epub 2023 Mar 22.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Escitalopram | Small molecule | 10 mg | — |
| Comparator | Escitalopram | Small molecule | 20 mg | — |