Drugs / M01ZH09
last change May 2022 re-read 9 days ago

M01ZH09

Vaccine

Developed for
typhoid fever
Investigated by
Emergent BioSolutions · Imperial College London · University of Maryland · University of Oxford · Wellcome Trust

Trials 2

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01405521 Oct 2011 → Dec 2015 typhoid fever University of Oxford Completed Missed primary
Phase 2 NCT00679172 May → Dec 2008 typhoid fever Emergent BioSolutions Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as M01ZH09 “Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a.” PMID 27533046 ↗ Aug 2016
1

“Immunogenicity, Safety and Tolerability of the Typhoid Fever Vaccine Candidate M01ZH09 in Healthy Adults” NCT00679172 ↗

Known as S. Typhi (Ty2 Delta aroC Delta ssaV) ZH9 “M01ZH09, S. Typhi (Ty2 Delta aroC Delta ssaV) ZH9, is a single oral dose typhoid vaccine with independently attenuating deletions.” PMID 20188175 ↗ Feb 2010
Modality Vaccine “single oral dose typhoid vaccine” PMID 20188175 ↗ Feb 2010
Route Oral “single oral dose” NCT00679172 ↗