Pentobarbital

also known as Auropan · Barpental · Biosedan · Diabutal · Embutal · Entobar · Etaminal sodium · Ethaminal sodium · +38 more

Small molecule

Developed for: traumatic brain injury · substance-related disorder
Investigated by: Children's Hospital Medical Center, Cincinnati · Fondo de Investigacion Sanitaria · Hospital Universitari Son Dureta · Johns Hopkins University · Orphan Medical

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	SODIUM PENTOBARBITAL	—	1973-08-31	fda.gov ↗

Trials 3 · a red edge is where a trial was stopped

today

US approved 1973

NCT02250820 · Ph 1 NCT00058955 · Ph 1 NCT00622570 · Ph 3

19731974197519761977197819791980198119821983198419851986198719881989199019911992199319941995199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 12 trials
Phase 1	NCT02250820	Nov 2014 → Dec 2017	heart disorder	Children's Hospital Medical Center, Cincinnati	Completed	No outcome recorded
Phase 1	NCT00058955	Aug 2003 → Mar 2005	substance abuse	Orphan Medical	Completed	No outcome recorded
Phase 31 trial
Phase 3	NCT00622570	May 2002 → Jul 2007	traumatic brain injury	Hospital Universitari Son Dureta	Terminated	No outcome recorded

Also used as a comparator or background therapy in 3 trials

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 1/21 trial
Phase 1/2	NCT00123578 Comparator	Aug 2004 → Aug 2008	substance-related disorder	University of California, Los Angeles	Withdrawn	No outcome recorded
Phase 31 trial
Phase 3	NCT00265616 Comparator	May 2006 → Mar 2010	—	Brigham and Women's Hospital	Terminated	No outcome recorded
Phase not applicable1 trial
—	NCT00878345 Comparator	Nov 2009 → Jun 2010	—	Washington University School of Medicine	Withdrawn	No outcome recorded

Evidence & citations 49 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

Field	Value	Cited text
Known as	Pentobarbital	ClinicalTrials.gov intervention name — accepted as the source's own label NCT00123578 ↗ 5 NCT00265616 ↗ NCT02250820 ↗ NCT00878345 ↗ NCT00058955 ↗ NCT00622570 ↗
Known as	Auropan	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Barpental	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Biosedan	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Diabutal	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Embutal	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Entobar	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Etaminal sodium	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Ethaminal sodium	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Euthanase	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Euthanyl	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Euthatal	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Isobarb	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Mebubarbital sodium	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Mebumal sodium	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Napental	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Narcoren	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Nembutal	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Nembutal sodium	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	NSC-10816	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	NSC-28708	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Pacifan	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Pental	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Pentobarbital cii	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	PENTOBARBITAL SODIUM	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Pentobarbital sodium salt	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Pentobarbitone	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Pentobarbitone sodium	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Pentonal	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Pentone	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Praecicalm	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Rs-pentobarbital sodium	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sagatal	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sodium ethaminal	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sodium nembutal	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sodium pental	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sodium pentobarbital	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sodium pentobarbitone	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sodium pentobarbiturate	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sodium-pent	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Soluble pentobarbital	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Somnopentyl	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Somnotol	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sopental	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Sotyl	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	V-pento	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Known as	Vetbutal	ChEMBL registry synonym — accepted as the source's own label CHEMBL448 ↗
Modality	Small molecule	— CHEMBL448 ↗
Route	Other	“as a continuous infusion” NCT00265616 ↗