Drugs / AO-252
last change May 2025 re-read 3 minutes ago

AO-252

targets TACC3 via inhibition

Developed for
metastatic malignant neoplasm in the brain
Investigated by
A2A Pharmaceuticals Inc.

Trials 1

2024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06136884 Nov 2023 → Jan 2027 expected metastatic malignant neoplasm in the brain A2A Pharmaceuticals Inc. Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-05-30 A2A Pharmaceuticals Inc. Results A2A TACC3 Program Clinical Progress in Womens Cancers a2apharma.com ↗
Significant (22% average over approximately 2 months) tumor reduction in 67% of the 4b (BID) cohort patients was observed.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as AO-252 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06136884 ↗
Action Inhibit “a Protein-Protein Interaction Inhibitor of TACC3” NCT06136884 ↗
Route Oral “administered oral tablets or capsules daily” NCT06136884 ↗
Target TACC3 “a Protein-Protein Interaction Inhibitor of TACC3” NCT06136884 ↗