drugset / Trial / NCT06136884

A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases

NCT06136884 ↗

Phase 1 Recruiting 86 enrolled A2A Pharmaceuticals Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to assess the safety, tolerability and efficacy of the study drug AO-252 and identify the best dose for use in future studies.

Timeline

Start
2023-11-02
Primary completion
2027-01-28
Completion
2028-01-27

Drugs

EvaluationDrugModalityDoseRoute
Subject AO-252 Unknown — Oral