Drugs / Bemarituzumab

Trials 16 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT06978062 Feb 2026 → Sep 2028 expected gastroesophageal cancer European Organisation for Research and Treatment of Cancer - EORTC Not yet recruiting No outcome recorded
Phase 1 NCT05267470 Mar 2022 → May 2024 non-small cell squamous lung carcinoma Amgen Terminated No outcome recorded
Phase 1 NCT03343301 Nov 2017 → Jan 2019 gastric cancer Five Prime Therapeutics, Inc. Completed No outcome recorded
Phase 1 NCT05913115 Jun 2017 → Jun 2018 gastroesophageal cancer Amgen Completed No outcome recorded
Phase 1 NCT02318329 Nov 2014 → Feb 2019 bladder transitional cell carcinoma, gastric cancer Five Prime Therapeutics, Inc. Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT07146919 Oct 2025 → Oct 2030 cervical cancer, endometrial carcinoma, ovarian cancer Centre Leon Berard Withdrawn No outcome recorded
Phase 1/2 NCT05325866 Sep 2022 → Jan 2026 cancer Amgen Terminated No outcome recorded
Phase 1/2 NCT05322577 May 2022 → Nov 2025 overdue gastric cancer, gastroesophageal junction adenocarcinoma Amgen Active not recruiting No outcome recorded
Phase 25 trials
Phase 2 NCT07470840 Feb 2027 → Feb 2029 expected renal cell adenocarcinoma Fujian Cancer Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06967987 Jan 2026 gastroesophageal adenocarcinoma Institut Cancerologie de l'Ouest Withdrawn No outcome recorded
Phase 2 NCT06680622 Mar 2025 → Sep 2027 expected gastroesophageal adenocarcinoma Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest Active not recruiting No outcome recorded
Phase 2 NCT03694522 Sep 2018 → Sep 2020 gastric cancer Five Prime Therapeutics, Inc. Completed No outcome recorded
Phase 2 NCT02213289 Jan 2015 → Feb 2020 adenocarcinoma University of Chicago Completed No outcome recorded
Phase 32 trials
Phase 3 NCT05111626 Mar 2022 → Oct 2025 gastric cancer, gastroesophageal junction adenocarcinoma Amgen Terminated No outcome recorded
Phase 3 NCT05052801 Mar 2022 → Jun 2025 gastric cancer, gastroesophageal junction adenocarcinoma Amgen Completed No outcome recorded
Phase not stated1 trial
NCT03801278 urinary bladder cancer Five Prime Therapeutics, Inc. No longer available No outcome recorded

Press releases naming this drug 3 releases

DateIssuerRelease
2025-06-30 Amgen AMGEN ANNOUNCES POSITIVE TOPLINE PHASE 3 RESULTS FOR BEMARITUZUMAB IN FIBROBLAST GROWTH FACTOR RECEPTOR 2b (FGFR2b) POSITIVE FIRST-LINE GASTRIC CANCER amgen.com
2021-06-04 Amgen Phase 2 Fight Trial Continues To Show Improved Overall Survival With Bemarituzumab Plus Chemotherapy In Patients With FGFR2b+ Gastric And Gastroesophageal Cancers amgen.com
2021-04-19 Amgen Amgen's Investigational Targeted Treatment Bemarituzumab Granted Breakthrough Therapy Designation amgen.com

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 19 sources stand behind the page.

FieldValueCited text
Known as Bemarituzumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT06978062
12

NCT03694522

NCT05111626

NCT06680622

NCT06967987

NCT05325866

NCT05267470

NCT07470840

NCT07146919

NCT05052801

NCT02213289

NCT05322577

NCT03343301

Known as FPA144 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05913115
2

NCT02318329

NCT03801278

Action Inhibit “anti-fibroblast growth factor receptor 2 isoform IIb (FGFR2b) monoclonal antibody bemarituzumab” PMID 36244398 Oct 2022
Modality Monoclonal antibody “a humanized monoclonal antibody selective for fibroblast growth factor receptor 2b (FGFR2b)” PMID 38308771 Feb 2024
Route Intravenous “administered by IV infusion” NCT02318329
Target FCGR3A “Low affinity immunoglobulin gamma Fc region receptor III-A binding agent” CHEMBL4802165
Target FGFR2 “fibroblast growth factor receptor 2b (FGFR2b)” PMID 38308771 Feb 2024