Drugs / CG200745
last change Jul 2026 re-read 3 minutes ago

CG200745

Small molecule

Developed for
cancer · pancreatic adenocarcinoma
Investigated by
CrystalGenomics, Inc. · CG Pharmaceuticals, Inc · Machaon Biotherapeutics, Inc.

Trials 4

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT05716919 Mar → Dec 2023 cancer, hematopoietic and lymphoid cell neoplasm Machaon Biotherapeutics, Inc. Unknown No outcome recorded
Phase 1 NCT05345912 Dec 2019 → Sep 2020 — CrystalGenomics, Inc. Completed No outcome recorded
Phase 1 NCT01226407 Sep 2010 → Feb 2013 cancer CrystalGenomics, Inc. Unknown No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05249101 Aug 2022 → Jun 2026 overdue pancreatic adenocarcinoma CG Pharmaceuticals, Inc Active not recruiting No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as CG200745 “Multiple Ascending Dose Study of CG200745 'Ivaltinostat' Oral Capsule” NCT05716919 ↗
1

NCT01226407 ↗

Known as CG 2 (HDAC INHIBITOR) ChEMBL registry synonym — accepted as the source's own label CHEMBL4297366 ↗
Known as CG-745 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05345912 ↗
Known as HDCG-0745 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297366 ↗
Known as Ivaltinostat ClinicalTrials.gov intervention name — accepted as the source's own label NCT05716919 ↗
1

NCT05249101 ↗

Known as J3.106.463E ChEMBL registry synonym — accepted as the source's own label CHEMBL4297366 ↗
Action Inhibit “inhibits enzymatic activity of histone deacetylase (HDAC).” NCT05249101 ↗
Modality Small molecule — CHEMBL4297366 ↗
Route Intravenous “Multiple administration (IV) over the cycles untile MTD/LTD” NCT01226407 ↗