Examine Maximum Tolerated Dose and Pharmacokinetic and Pharmacodynamic Profile

Summary

Open label, single dose and phase I study. The primary objective: To determine the maximum tolerated dose in Single dose The secondary objective: to evaluate the toxicity in administration to determine desirable dosing amount for phase II to evaluate tumor response in progressive solid cancer patients to evaluate pharmacokinetic/ pharmacodynamic profile.

Timeline

Start

2010-09

Primary completion

2013-02

Completion

2013-02

Drugs

Indications