Drugs / DO-2
last change Sep 2025 re-read 3 minutes ago

DO-2

targets MET via inhibition

Developed for
hereditary papillary renal cell carcinoma · non-small cell lung carcinoma
Investigated by
DeuterOncology

Trials 1

20232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05752552 Dec 2022 → Sep 2027 expected hereditary papillary renal cell carcinoma, non-small cell lung carcinoma DeuterOncology Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-09-08 DeuterOncology Results Promising Phase I Results for DO-2 MET Kinase Inhibitor deuteroncology.com ↗
RECIST 1.1 Partial responses (>30% reduction) were observed in 2 out of these 10 patients.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as DO-2 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05752552 ↗
Action Inhibit “Deuterated MET kinase inhibitor” NCT05752552 ↗
Route Oral “Oral administration” NCT05752552 ↗
Target MET “Deuterated MET kinase inhibitor” NCT05752552 ↗