drugset / Trial / NCT05752552

Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients With Advanced or Refractory Solid Tumours

NCT05752552 ↗

Phase 1 Recruiting 55 enrolled DeuterOncology
Non-randomizedSequentialOpen-labelTreatment

Summary

This study is a first-in-human, open-label, 2-part, Phase 1 dose escalation study of DO-2, administered orally to patients with advanced or refractory solid tumours, with MET aberrations, and no available, approved therapeutic alternative. The dose escalation is completed, Part 2 of the study is ongoing.

Timeline

Start
2022-12-20
Primary completion
2027-09
Completion
2028-09

Drugs

EvaluationDrugModalityDoseRoute
Subject DO-2 Unknown — Oral