Drugs / doxifluridine
doxifluridine
also known as
5'-deoxy-5-fluorouridine (5'-dfur) · Capecitabine related compound b · Doxifluridina · Flutron · Fulturon · Furtulon · NSC-758890 · RO 219738
Small molecule targets TYMS via inhibition
Trials 0
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 32 trials | ||||||
| Phase 3 | NCT00296335 Comparator | Feb 2002 → Nov 2007 | gastric adenocarcinoma | Asan Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT00296322 Comparator | Oct 2001 → Dec 2007 | gastric cancer | Asan Medical Center | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT01401075 Background | Mar 2006 → Apr 2008 | gastric cancer | Abnoba GmbH | Completed | No outcome recorded |
Evidence & citations 13 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | doxifluridine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01401075 ↗ |
| Known as | 5'-deoxy-5-fluorouridine (5'-dfur) | ChEMBL registry synonym — accepted as the source's own label CHEMBL1130 ↗ |
| Known as | Capecitabine related compound b | ChEMBL registry synonym — accepted as the source's own label CHEMBL1130 ↗ |
| Known as | Doxifluridina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1130 ↗ |
| Known as | Flutron | ChEMBL registry synonym — accepted as the source's own label CHEMBL1130 ↗ |
| Known as | Fulturon | ChEMBL registry synonym — accepted as the source's own label CHEMBL1130 ↗ |
| Known as | Furtulon | ChEMBL registry synonym — accepted as the source's own label CHEMBL1130 ↗ |
| Known as | NSC-758890 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1130 ↗ |
| Known as | RO 219738 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1130 ↗ |
| Action | Inhibit | “Thymidylate synthase inhibitor” CHEMBL1130 ↗ |
| Modality | Small molecule | — CHEMBL1130 ↗ |
| Route | Oral | “Doxifluridine 460-600mg/m2/day per oral for 3 months” NCT00296322 ↗ |
| Target | TYMS | “Thymidylate synthase inhibitor” CHEMBL1130 ↗ |