drugset / Trial / NCT00296322
Trial of Adjuvant Chemotherapy for Gastric Cancer
Phase 3
Completed
528 enrolled
Asan Medical Center
Hallym University Medical Center · collabUlsan University Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is designed to evaluate the efficacy of the intraperitoneal chemotherapy with early mitomycin administration and adding cisplatin to prolonged treatment with doxifluridine compared to mitomycin plus doxifluridine in resected advanced gastric cancer.
Timeline
- Start
- 2001-10
- Primary completion
- 2007-12
- Completion
- 2010-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cisplatin | Other / unclassified | 60 mg/m2 | Intravenous |
| Comparator | Mitomycin C | Other / unclassified | 15 mg/m2 | Intravenous |
| Comparator | Mitomycin C | Other / unclassified | 20 mg/m2 | Intravenous |
| Comparator | doxifluridine | Small molecule | 460 mg/m2 | Oral |
| Comparator | doxifluridine | Small molecule | 600 mg/m2 | Oral |