Drugs / arpraziquantel
last change 10 days ago re-read 9 days ago

arpraziquantel

Small molecule

Developed for
opisthorchiasis · schistosomiasis
Investigated by
Merck KGaA, Darmstadt, Germany · Jennifer Keiser · Lao Tropical and Public Health Institute

Trials 3

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02271984 Oct → Dec 2014 — Merck KGaA, Darmstadt, Germany Completed No outcome recorded
Phase 21 trial
Phase 2 NCT07262814 Jul → Oct 2026 expected opisthorchiasis Jennifer Keiser Not yet recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT03845140 Sep 2019 → Oct 2021 schistosomiasis Merck KGaA, Darmstadt, Germany Completed No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2025-03-04 Merck KGaA, Darmstadt, Germany First Preschool-Aged Child Receives Arpraziquantel for the Treatment of Schistosomiasis emdgroup.com ↗

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as arpraziquantel “Efficacy, safety, and palatability of arpraziquantel (L-praziquantel) orodispersible tablets in children aged 3 months to 6 years infected with Schistosoma in Côte d'Ivoire and...” PMID 36893784 ↗ Mar 2023
1

“ascending doses of arpraziquantel in children infected with Opisthorchis viverrini” NCT07262814 ↗

Known as (r)-(-)-praziquantel ChEMBL registry synonym — accepted as the source's own label CHEMBL1235551 ↗
Known as Arprazicuantel ChEMBL registry synonym — accepted as the source's own label CHEMBL1235551 ↗
Known as L-praziquantel “Efficacy, safety, and palatability of arpraziquantel (L-praziquantel) orodispersible tablets in children aged 3 months to 6 years infected with Schistosoma in Côte d'Ivoire and...” PMID 36893784 ↗ Mar 2023
Known as L-pzq ChEMBL registry synonym — accepted as the source's own label CHEMBL1235551 ↗
Known as MSC2499550A ClinicalTrials.gov intervention name — accepted as the source's own label NCT02271984 ↗
Modality Small molecule — CHEMBL1235551 ↗
Route Oral “Subjects will receive a single oral dose of MSC2499550A formulation at 20 mg/kg dispersed in water under fed condition in one of the intervention periods.” NCT02271984 ↗