Drugs / salicylic acid
salicylic acid
also known as
2-hydroxybenzoic acid · Acnisal · Bazuka · Compound v · Compound w · Cuplex verruca · Dr. scholl's callus removers · Duofilm · +28 more
Trials 21 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT02812719 | Jul → Dec 2018 | hyperpigmentation of the skin | Boston Medical Center | Withdrawn | No outcome recorded |
| Phase 12 trials | ||||||
| Phase 1 | NCT05497323 | Aug → Nov 2022 | acne | Indonesia University | Unknown | No outcome recorded |
| Phase 1 | NCT05588999 | Mar → Aug 2022 | plantar wart | Combined Military Hospital Abbottabad | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT00361322 | Apr 2005 → Jan 2006 | acne | Hadassah Medical Organization | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT01358851 | Apr 2011 → Mar 2012 | actinic keratosis | Almirall, S.A. | Completed | No outcome recorded |
| Phase 2 | NCT01228656 | Sep 2006 → Oct 2010 | psoriasis | Azidus Brasil | Suspended | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT02289768 | Oct 2014 → Sep 2015 | actinic keratosis | Almirall, S.A. | Completed | No outcome recorded |
| Phase 3 | NCT01229085 | Sep 2006 → Oct 2007 | psoriasis | Azidus Brasil | Completed | No outcome recorded |
| Phase 47 trials | ||||||
| Phase 4 | NCT07401342 | Nov → Dec 2023 | — | Instituto de Oftalmología Fundación Conde de Valenciana | Completed | No outcome recorded |
| Phase 4 | NCT05536193 | Sep 2022 → Sep 2023 | acne | Assiut University | Unknown | No outcome recorded |
| Phase 4 | NCT05446402 | Jun 2022 → May 2023 | acne | Northwestern University | Completed | No outcome recorded |
| Phase 4 | NCT06307223 | Jun 2022 → Sep 2023 | folliculitis | Second Affiliated Hospital of Xi'an Jiaotong University | Completed | No outcome recorded |
| Phase 4 | NCT03832647 | Feb 2019 → Feb 2020 | acne | Vichy Laboratoires | Completed | No outcome recorded |
| Phase 4 | NCT01706263 | Aug → Nov 2009 | acne | Stiefel, a GSK Company | Completed | No outcome recorded |
| Phase 4 | NCT00944216 | Jun 2009 → Jan 2010 | keratosis pilaris | Wright State University | Terminated | No outcome recorded |
| Phase not applicable6 trials | ||||||
| — | NCT06969300 | Dec 2023 → Nov 2024 | rosacea | Second Affiliated Hospital of Xi'an Jiaotong University | Completed | No outcome recorded |
| — | NCT04889703 | Dec 2022 → Dec 2023 | rosacea | University of Texas Southwestern Medical Center | Withdrawn | No outcome recorded |
| — | NCT04601259 | Oct 2020 → Jan 2021 | — | Orkla Care AB | Completed | No outcome recorded |
| — | NCT03156062 | Jul → Oct 2017 | erythematosquamous dermatosis | Assiut University | Unknown | No outcome recorded |
| — | NCT00848666 | Apr 2009 → Apr 2010 | tinea pedis | Hillel Yaffe Medical Center | Unknown | No outcome recorded |
| — | NCT00848744 | Feb → Aug 2008 | acne | Northwestern University | Completed | No outcome recorded |
Also used as a comparator or background therapy in 16 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT07396714 Comparator | Feb 2026 → Feb 2027 expected | skin disorder caused by infection | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 24 trials | ||||||
| Phase 2 | NCT04429308 Comparator | Aug 2026 → Dec 2027 expected | actinic keratosis | Northwestern University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07329907 Comparator | Dec 2023 → Jun 2024 | common wart, human papilloma virus infection | Benha University | Completed | No outcome recorded |
| Phase 2 | NCT02352987 Comparator | Mar → Sep 2015 | poisoning | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Completed | No outcome recorded |
| Phase 2 | NCT01914627 Comparator | Aug 2013 → Jan 2014 | psoriasis | G. Pohl-Boskamp GmbH & Co. KG | Completed | No outcome recorded |
| Phase 2/32 trials | ||||||
| Phase 2/3 | NCT05862441 Comparator | Jan 2018 → Dec 2019 | common wart | University of Antwerp | Completed | No outcome recorded |
| Phase 2/3 | NCT02151630 Comparator | May → Sep 2014 | plantar wart | Isfahan University of Medical Sciences | Unknown | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT06775314 Comparator | Mar → May 2025 overdue | acne | Indonesia University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT03071549 Comparator | Apr → Aug 2016 | acne | Cairo University | Completed | No outcome recorded |
| Phase 44 trials | ||||||
| Phase 4 | NCT02755545 Comparator | May 2016 → Apr 2017 | acne | Galderma R&D | Completed | No outcome recorded |
| Phase 4 | NCT02052752 Comparator | Feb → May 2014 | skin disorder | GlaxoSmithKline | Completed | No outcome recorded |
| Phase 4 | NCT01139749 Comparator | Oct 2011 → Jul 2012 | seborrheic dermatitis | Federal University of São Paulo | Unknown | No outcome recorded |
| Phase 4 | NCT00616239 Comparator | Jan 2008 → Mar 2018 | hyperpigmentation of the skin | University of Texas Southwestern Medical Center | Completed | No outcome recorded |
| Phase not applicable3 trials | ||||||
| — | NCT07535424 Comparator | Nov 2024 → Oct 2025 | otomycosis | Mayo Hospital Lahore | Completed | No outcome recorded |
| — | NCT05712837 Comparator | Jun → Nov 2022 | acne | Combined Military Hospital Abbottabad | Completed | No outcome recorded |
| — | NCT01731756 Background | Jan → Dec 2013 | keratosis | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Completed | No outcome recorded |
Evidence & citations 40 cited values
Every value below carries the sentence it was read from. 38 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | salicylic acid | “Chemical peels consists of a combination of Jessner's Solution: Composed of Salicylic Acid (14%), Medical Grade Lactic Acid (14%), Medical Grade Resorcinol (14%), Denatured...” NCT04429308 ↗36“combination cream consist of Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic acid will be given to subjects to be applied every...” NCT06775314 ↗ “They will receive an application of salicylic acid to the facial surface through continuous massaging for a duration of five minutes, facilitating the exfoliation of the...” NCT07401342 ↗ “A commercial product containing 2% salicylic acid that reportedly improves acne lesions was applied on participant's face once-daily at approximately the same time on Days 0,...” NCT02052752 ↗ “The combination cream consists of Salicylic Acid, Aqua Posae Filiformis, Niacinamide, Lipohydroxy Acid, Procerad and Zinc PCA, were applied every morning by group 2 and group 3.” NCT05497323 ↗ “Efficacy of low-dose (0.5%) 5-fluorouracil with 10% salicylic acid (5-FU/SA) has been shown in randomized comparative trials of hyperkeratotic lesions of various grades.” PMID 25257941 ↗ Sep 2014 “Salicylic acid 1.0% creams (Formulation A and Formulation B) will be evaluated to detect any differences in their response for safety and efficacy.” NCT00848744 ↗ “One time immersion of the feet in a liquid containing water, alcohol, vinegar, benzoic acid and salicylic acid for a total of 30 minutes.” NCT00848666 ↗ “Salkera emollient foam is a keratolytic foam containing 6% salicylic acid in an aqueous based emollient foam vehicle.” NCT00944216 ↗ “Salicylic acid (SA) formulations are the most commonly used preparations in the treatment of warts.” NCT05862441 ↗ “1. Clarifying Gel Cleanser - SA Formula (2% Salicylic Acid)” NCT05446402 ↗ “Product B (salicylic acid)” NCT02755545 ↗ |
| Known as | 2-hydroxybenzoic acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Acnisal | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Bazuka | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Compound v | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Compound w | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Cuplex verruca | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Dr. scholl's callus removers | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Duofilm | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Edinburgh | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Erytex | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | FEMA NO. 3985 | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Freezone | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Gppe paint | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Jadit | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | K-557 | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Keralyt | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Lamivudine impurity, salicylic acid- | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Lamivudine related compound salicylic acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Metanium | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Necol | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Noxacorn | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | NSC-180 | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Occlusal | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Phiso-clear | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Phytex | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Phytocil | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Posalfilin | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Product B | “Product B (salicylic acid)” NCT02755545 ↗ |
| Known as | Pyralvex | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Salactol | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Salatac | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Salicylic acid rs | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Thwart | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Toepedo | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Verrugon | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Known as | Wartex | ChEMBL registry synonym — accepted as the source's own label CHEMBL424 ↗ |
| Action | Inhibit | “SA inhibits the arachidonic acid cascade leading to a decrease in inflammatory lesions .” NCT05536193 ↗ |
| Modality | Small molecule | “SA is an organic acid that destroys epidermal cells and softens hyperkeratotic epidermis.” NCT05862441 ↗ |
| Route | Topical | “Topical Clindamycin Salicylic Acid Preparation for the Treatment of Acne Vulgaris” NCT00361322 ↗ |