Drugs / HAEMOPHILUS INFLUENZAE TYPE B CAPSULAR POLYSACCHARIDE MENINGOCOCCAL OUTER MEMBRANE PROTEIN CONJUGATE ANTIGEN
last change Oct 2023 re-read 2 minutes ago

HAEMOPHILUS INFLUENZAE TYPE B CAPSULAR POLYSACCHARIDE MENINGOCOCCAL OUTER MEMBRANE PROTEIN CONJUGATE ANTIGEN

also known as PedvaxHIB

Vaccine

Developed for
bacterial infectious disease · haemophilus infectious disease
Investigated by
Merck Sharp & Dohme LLC · MCM Vaccines B.V.

Trials 2 · a red edge is where a trial was stopped

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 31 trial
Phase 3 NCT01337167 Apr 2011 → May 2013 bacterial infectious disease, viral infectious disease Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 41 trial
Phase 4 NCT00289913 Apr 2006 → Jun 2010 hepatitis A virus infection Merck Sharp & Dohme LLC Completed No outcome recorded
Also used as a comparator or background therapy in 6 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT01545375 Background May 2012 → Jul 2016 streptococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT00134719 Comparator Apr 2005 → Jul 2006 haemophilus infectious disease, meningococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 33 trials
Phase 3 NCT01978093 Comparator Feb 2014 → Mar 2016 haemophilus infectious disease, meningococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00345683 Comparator Jul 2007 → Sep 2008 haemophilus infectious disease, meningococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00289783 Comparator Feb 2006 → Aug 2007 haemophilus infectious disease, meningococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 41 trial
Phase 4 NCT04978818 Comparator Jan 2022 → Oct 2023 haemophilus infectious disease Johns Hopkins Bloomberg School of Public Health Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as HAEMOPHILUS INFLUENZAE TYPE B CAPSULAR POLYSACCHARIDE MENINGOCOCCAL OUTER MEMBRANE PROTEIN CONJUGATE ANTIGEN ChEMBL registry synonym — accepted as the source's own label CHEMBL4298071
Known as PedvaxHIB ClinicalTrials.gov intervention name — accepted as the source's own label NCT00289913
7

NCT00134719

NCT01978093

NCT01545375

NCT00345683

NCT01337167

NCT04978818

NCT00289783

Modality Vaccine “ActHIB, PedvaxHIB vaccines were administered intramuscularly in the right upper thigh and Pediarix vaccine in the left upper thigh.” NCT00289783
Route Intramuscular “ActHIB, PedvaxHIB vaccines were administered intramuscularly in the right upper thigh and Pediarix vaccine in the left upper thigh.” NCT00289783