drugset / Trial / NCT01978093

Immunogenicity, Safety and Reactogenicity Study of GlaxoSmithKline (GSK) Biologicals' Hib-MenCY-TT (MenHibrix®) Vaccine Compared to Merck & Co, Inc. PedvaxHIB Vaccine in Healthy Infants and Toddlers 12 to 15 Months of Age

NCT01978093

Phase 3 Completed 600 enrolled GlaxoSmithKline
RandomizedParallel-groupOpen-labelPrevention

Summary

The purpose of this study is to evaluate the safety, reactogenicity and immunogenicity of GSK Biologicals' Hib-MenCY-TT (MenHibrix®) vaccine co-administered with Rotarix, Prevnar 13 and Havrix as compared to PedvaxHIB co-administered with Rotarix, Prevnar 13 and Havrix in infants and toddlers.

Timeline

Start
2014-02-01
Primary completion
2016-03-18
Completion
2016-03-18

Drugs

EvaluationDrugModalityDoseRoute
Comparator HAEMOPHILUS INFLUENZAE TYPE B CAPSULAR POLYSACCHARIDE MENINGOCOCCAL OUTER MEMBRANE PROTEIN CONJUGATE ANTIGEN Vaccine Intramuscular
Subject Hib-MenCY-TT Vaccine Intramuscular
Background Havrix Vaccine Intramuscular
Background Pediarix Vaccine Intramuscular
Background Prevnar 13 Vaccine Intramuscular
Background Rotarix Vaccine Oral