| Phase 03 trials |
|
Phase 0
|
NCT03571282 |
Jun 2018 → Jun 2019 |
hemangioma of choroid |
Sun Yat-sen University |
Unknown
|
No outcome recorded
|
|
Phase 0
|
NCT03426540 |
Jan 2017 → Mar 2018 |
proliferative diabetic retinopathy |
Tianjin Medical University Eye Hospital |
Completed
|
No outcome recorded
|
|
Phase 0
|
NCT03973125 |
Aug 2014 → Jan 2020 |
hemangioma of choroid |
Sun Yat-sen University |
Unknown
|
No outcome recorded
|
| Phase 11 trial |
|
Phase 1
|
NCT04215393 |
Jul 2019 → Apr 2020 |
corneal neovascularization |
Chengdu Kanghong Biotech Co., Ltd. |
Unknown
|
No outcome recorded
|
| Phase 1/22 trials |
|
Phase 1/2
|
NCT01324869 |
Apr 2010 → Feb 2012 |
diabetic macular edema |
Chengdu Kanghong Biotech Co., Ltd. |
Completed
|
No outcome recorded
|
|
Phase 1/2
|
NCT01242254 |
Aug 2009 → Mar 2010 |
wet macular degeneration |
Chengdu Kanghong Biotech Co., Ltd. |
Completed
|
No outcome recorded
|
| Phase 28 trials · 1 missed |
|
Phase 2
|
NCT05642793 |
Apr 2022 → Sep 2023 |
proliferative diabetic retinopathy |
Peking University Third Hospital |
Unknown
|
No outcome recorded
|
|
Phase 2
|
NCT04990271 |
Jul 2021 → Apr 2023 |
retinoblastoma |
Chengdu Kanghong Biotech Co., Ltd. |
Unknown
|
No outcome recorded
|
|
Phase 2
|
NCT04782115 |
Mar 2021 → Jul 2023 |
diabetic macular edema |
RemeGen Co., Ltd. |
Completed
|
Missed primary
|
|
Phase 2
|
NCT02934841 |
Nov 2016 → Mar 2018 |
choroidal neovascularization, uveitis |
Chongqing Medical University |
Unknown
|
No outcome recorded
|
|
Phase 2
|
NCT02857517 |
Jun 2016 → Jun 2018 |
choroidal neovascularization |
Jiao Mingfei |
Unknown
|
No outcome recorded
|
|
Phase 2
|
NCT01809236 |
May 2012 → Nov 2013 |
retinal vein occlusion |
Chengdu Kanghong Biotech Co., Ltd. |
Unknown
|
No outcome recorded
|
|
Phase 2
|
NCT02098720 |
Dec 2011 → Mar 2014 |
wet macular degeneration |
Chengdu Kanghong Biotech Co., Ltd. |
Unknown
|
No outcome recorded
|
|
Phase 2
|
NCT01157715 |
May 2010 → Jan 2012 |
wet macular degeneration |
Chengdu Kanghong Biotech Co., Ltd. |
Completed
|
No outcome recorded
|
| Phase 2/32 trials |
|
Phase 2/3
|
NCT04296838 |
Oct 2019 → Apr 2020 |
macular retinal edema, uveitis |
Peking Union Medical College Hospital |
Terminated
|
No outcome recorded
|
|
Phase 2/3
|
NCT05539235 |
Nov 2018 → Aug 2023 |
wet macular degeneration |
First Affiliated Hospital of Chongqing Medical University |
Unknown
|
No outcome recorded
|
| Phase 37 trials · 1 met primary |
|
Phase 3
|
NCT03630952 |
Dec 2018 → Sep 2020 |
wet macular degeneration |
Chengdu Kanghong Biotech Co., Ltd. |
Terminated
|
No outcome recorded
|
|
Phase 3
|
NCT03577899 |
Sep 2018 → Sep 2020 |
wet macular degeneration |
Chengdu Kanghong Biotech Co., Ltd. |
Terminated
|
No outcome recorded
|
|
Phase 3
|
NCT03223714 |
May 2016 → Apr 2020 |
central retinal vein occlusion, macular retinal edema |
Chengdu Kanghong Biotech Co., Ltd. |
Completed
|
No outcome recorded
|
|
Phase 3
|
NCT03108352 |
Apr 2016 → Apr 2020 |
macular retinal edema, retinal vein occlusion |
Chengdu Kanghong Biotech Co., Ltd. |
Completed
|
No outcome recorded
|
|
Phase 3
|
NCT02194634 |
Jul 2014 → Dec 2016 |
diabetic macular edema |
Chengdu Kanghong Biotech Co., Ltd. |
Unknown
|
Met primary
|
|
Phase 3
|
NCT01809223 |
Aug 2012 → Feb 2014 |
choroidal neovascularization |
Chengdu Kanghong Biotech Co., Ltd. |
Unknown
|
No outcome recorded
|
|
Phase 3
|
NCT01436864 |
Aug 2011 → Dec 2012 |
wet macular degeneration |
Chengdu Kanghong Biotech Co., Ltd. |
Completed
|
No outcome recorded
|
| Phase 48 trials · 1 met primary · 1 missed |
|
Phase 4
|
NCT06305143 |
Apr 2024 → Jun 2025 overdue |
diabetic macular edema |
Shanghai Eye Disease Prevention and Treatment Center |
Active not recruiting
|
No outcome recorded
|
|
Phase 4
|
NCT04380974 |
Jun → Oct 2020 |
perifoveal exudative vascular anomalous complex |
Xiaodong Sun |
Unknown
|
No outcome recorded
|
|
Phase 4
|
NCT03506750 |
Jun 2017 → Sep 2018 |
perifoveal exudative vascular anomalous complex, proliferative diabetic retinopathy |
The First Affiliated Hospital with Nanjing Medical University |
Unknown
|
No outcome recorded
|
|
Phase 4
|
NCT03244657 |
Apr 2017 → Oct 2019 |
— |
Chengdu Kanghong Biotech Co., Ltd. |
Unknown
|
No outcome recorded
|
|
Phase 4
|
NCT02821520 |
Jan 2017 → Jun 2019 |
— |
The Eye Hospital of Wenzhou Medical University |
Completed
|
Met primary
|
|
Phase 4
|
NCT02802657 |
Sep 2016 → Sep 2020 |
age-related macular degeneration |
Xiaodong Sun |
Unknown
|
Missed primary
|
|
Phase 4
|
NCT02816710 |
Jul 2016 → Sep 2017 |
proliferative diabetic retinopathy, retinal detachment |
Ruijin Hospital |
Completed
|
No outcome recorded
|
|
Phase 4
|
NCT03159884 |
Oct 2015 → Jun 2018 |
choroidal neovascularization |
Chengdu Kanghong Biotech Co., Ltd. |
Unknown
|
No outcome recorded
|
| Phase not applicable4 trials |
| — |
NCT06717412 |
Nov 2024 → Dec 2026 expected |
retinopathy of prematurity |
Wang Yusheng |
Recruiting
|
No outcome recorded
|
| — |
NCT02911311 |
Oct 2019 → Dec 2022 |
proliferative diabetic retinopathy |
Sun Yat-sen University |
Unknown
|
No outcome recorded
|
| — |
NCT03971162 |
Jun 2019 → Dec 2022 |
choroidal neovascularization |
Zhongshan Ophthalmic Center, Sun Yat-sen University |
Completed
|
No outcome recorded
|
| — |
NCT03863535 |
Jan 2019 → Jan 2021 |
diabetes mellitus, severe nonproliferative diabetic retinopathy |
Ruijin Hospital |
Unknown
|
No outcome recorded
|
| Comparator or background therapy5 trials |
|
Phase 4
|
NCT07133438 Background |
Aug 2025 → May 2027 expected |
retinal vein occlusion |
First Affiliated Hospital of Chongqing Medical University |
Recruiting
|
No outcome recorded
|
|
Phase 4
|
NCT02577107 Comparator |
Jan → Jul 2016 |
age-related macular degeneration |
Novartis Pharmaceuticals |
Completed
|
No outcome recorded
|
| — |
NCT07144865 Comparator |
Dec 2024 → Apr 2025 |
proliferative diabetic retinopathy |
Bojie Hu |
Completed
|
No outcome recorded
|
| — |
NCT05728476 Comparator |
Mar 2024 → Sep 2025 overdue |
diabetic macular edema |
Tianjin Medical University Eye Hospital |
Recruiting
|
No outcome recorded
|
| — |
NCT04627402 Background |
Nov 2020 → Jun 2021 |
diabetic macular edema, type 2 diabetes mellitus |
Zhongshan Ophthalmic Center, Sun Yat-sen University |
Unknown
|
No outcome recorded
|