drugset / Trial / NCT02934841

Conbercept in Choroidal Neovascularization Secondary to Uveitis

NCT02934841

Phase 2 Unknown 40 enrolled Chongqing Medical University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The investigators hypothesize that it is safe and effective to treat patients with choroidal neovascularisation (abnormal blood vessels growing under the retina) secondary to uveitis with Conbercept. This will be a randomized, placebo-controlled trial. 20 patients will receive three injections of Conbercept into the affected eye (and repeated injections if required), and 20 patients will receive three sham injections requiring no needle stick, but making the patient unaware of whether or not he received active treatment. Outcome of the two treatment groups will be compared after one year.

Timeline

Start
2016-11
Primary completion
2018-03
Completion
2018-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Conbercept Protein / enzyme biologic 0.5 mg Intravitreal