Drugs / Micronized purified flavonoid fraction
last change Oct 2025 re-read 2 minutes ago

Micronized purified flavonoid fraction

also known as Daflon · MPFF · Venixxa
Developed for
anal fistula · rectal disorder · pelvic congestion syndrome · post-thrombotic syndrome
Investigated by
Chiang Mai University · Taipei Medical University Shuang Ho Hospital

Trials 2 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 41 trial
Phase 4 NCT06184438 Dec 2023 → Jan 2025 anal fistula Taipei Medical University Shuang Ho Hospital Completed No outcome recorded
Phase not applicable1 trial
NCT06363513 Apr → May 2024 rectal disorder Chiang Mai University Unknown No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 32 trials
Phase 3 NCT06584799 Comparator Dec 2024 → Jan 2025 overdue pelvic congestion syndrome Pirogov Russian National Research Medical University Recruiting No outcome recorded
Phase 3 NCT03833024 Comparator Feb 2022 → Mar 2024 post-thrombotic syndrome Sir Mortimer B. Davis - Jewish General Hospital Unknown No outcome recorded
Phase not applicable1 trial
NCT06560294 Comparator Aug 2024 → Oct 2025 overdue pelvic congestion syndrome Tanta University Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Micronized purified flavonoid fraction Micronized Purified Flavonoid Fraction (MPFF), integral to hemorrhoid treatment, has been scrutinized for its ability to mitigate pathogenic processes culminating in acute bleeding.” NCT06363513
4

NCT06584799

NCT06560294

NCT06184438

NCT03833024

Known as Daflon “Patients will receive micronized purified flavonoid fraction (Daflon ®), 500 mg twice/daily for 3 months.” NCT06560294
1

“Micronized purified flavonoid fraction(Daflon 1000mg)” NCT06184438

Known as MPFF “Micronized Purified Flavonoid Fraction (MPFF, Venixxa), a venoactive drug, has been reported to be effective in reducing venous symptoms and signs and improving QOL in patients...” NCT03833024
Known as Venixxa “Micronized Purified Flavonoid Fraction (MPFF, Venixxa), a venoactive drug, has been reported to be effective in reducing venous symptoms and signs and improving QOL in patients...” NCT03833024
Route Oral “1000 mg of oral MPFF (Venixxa, one 500mg tablet BID)” NCT03833024