Drugs / Sulpiride
Sulpiride
also known as
Abilit · Aiglonyl · Coolspan · Dobren · Dogmatil · Dogmatyl · Dolmatil · Guastil · +17 more
Small molecule targets DRD2 via inhibition
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 32 trials | ||||||
| Phase 3 | NCT02374567 | Jan 2015 → Jun 2017 | anxiety disorder, dementia, depressive disorder, schizophrenia +1 | Hannover Medical School | Terminated | No outcome recorded |
| Phase 3 | NCT01765829 | Nov 2012 → Nov 2015 | psychotic disorder | Fundación Pública Andaluza Progreso y Salud | Unknown | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT04583111 | Mar 2020 → Mar 2022 | — | RenJi Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02307396 | Feb 2015 → Jun 2016 | schizoaffective disorder, schizophrenia | Technical University of Munich | Completed | No outcome recorded |
| Phase not applicable2 trials | ||||||
| — | NCT05208294 | Dec 2021 → Sep 2023 | — | Philipps University Marburg | Completed | No outcome recorded |
| — | NCT01777685 | Jan 2013 | — | Damanhour University | Completed | No outcome recorded |
Also used as a comparator or background therapy in 5 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial | ||||||
| Phase 3 | NCT02749747 Comparator | Jun 2014 → Oct 2017 | — | Hospital de Clinicas de Porto Alegre | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT00654576 Comparator | Feb 2005 → Dec 2007 | schizophrenia | Central South University | Completed | No outcome recorded |
| Phase not applicable3 trials | ||||||
| — | NCT05884671 Comparator | Sep 2021 → Jul 2022 | — | Donders Centre for Cognitive Neuroimaging | Completed | No outcome recorded |
| — | NCT01896349 Background | Apr 2013 → Aug 2014 | — | Hospital de Clinicas de Porto Alegre | Unknown | No outcome recorded |
| — | NCT00280501 Comparator | Aug 2005 → Aug 2006 | — | Medical University of Vienna | Completed | No outcome recorded |
Evidence & citations 30 cited values
Every value below carries the sentence it was read from. 12 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Sulpiride | “Drugs: Aripiprazole, Olanzapine, Zuclopenthixol, Clotiapine, Flupentixol, Risperidone, Sulpiride, Trifluoperazine, Haloperidol, Quetiapine, Paliperidone, Chlorpromazine,...” NCT01765829 ↗ |
| Known as | Abilit | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Aiglonyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Coolspan | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Dobren | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Dogmatil | “Sulpiride (Dogmatil 200mg-tablet, Synthélabo Groupe, Le Plessis Robinson, France) Dose: one half of 200 mg tablet oral single dose” NCT00280501 ↗ |
| Known as | Dogmatyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Dolmatil | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Guastil | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Meresa | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Mirbanil | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Misulvan | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | N05AL01 | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Neogama | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | NSC-757850 | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Omperan | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Pyrikappl | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | RD-1403 | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Sernevin | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Splotin | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Sulpirida | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Sulpitil | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Sulpor | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Sursumid | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Synedil | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Known as | Trilan | ChEMBL registry synonym — accepted as the source's own label CHEMBL26 ↗ |
| Action | Inhibit | “Sulpiride is a selective D2-recptor antagonist which presumably elevates DA levels in low doses and has been used as an antidepressant.” NCT05208294 ↗1“Dopamine D2 receptor antagonist” CHEMBL26 ↗ |
| Modality | Small molecule | “The substituted benzamide sulpiride is a selective D2-receptor antagonist” NCT05208294 ↗ |
| Route | Oral | “one half of 200 mg tablet oral single dose” NCT00280501 ↗ |
| Target | DRD2 | “Dopamine D2 receptor antagonist” CHEMBL26 ↗ |