Drugs / Xenin-25
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT02204813 | Jul 2014 → Nov 2015 | — | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT01951729 | Mar 2013 → May 2015 | prediabetes syndrome | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT01951716 | Jan 2013 → Jul 2018 | — | Washington University School of Medicine | Withdrawn | No outcome recorded |
| Phase 1 | NCT00949663 | Oct 2009 → Feb 2014 | type 2 diabetes mellitus | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT00798915 | Dec 2008 → Dec 2012 | diabetes mellitus | Washington University School of Medicine | Completed | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Xenin-25 | “Xenin-25 (Xen) is a neurotensin-related peptide secreted by a subset of enteroendocrine cells located in the proximal small intestine.” PMID 27288245 ↗ Jun 2016 |
| Known as | Xen | “Xenin-25 (Xen) is a neurotensin-related peptide secreted by a subset of glucose-dependent insulinotropic polypeptide (GIP)-producing enteroendocrine cells.” PMID 24356886 ↗ Dec 20132“Xenin-25 (Xen) is a neurotensin-related peptide secreted by a subset of enteroendocrine cells located in the proximal small intestine.” PMID 27288245 ↗ Jun 2016 “Xenin-25 (Xen) is a 25-amino acid neurotensin-related peptide that activates neurotensin receptor-1 (NTSR1).” PMID 24183983 ↗ Oct 2013 |
| Action | Activate | “activates neurotensin receptor-1 (NTSR1)” PMID 24183983 ↗ Oct 2013 |
| Modality | Peptide | “Xenin-25 (Xen) is a 25-amino acid neurotensin-related peptide” PMID 24183983 ↗ Oct 2013 |
| Route | Intravenous | “Intravenous infusion of xenin-25 (4 pmoles x kg-1 x min-1) in 1% human albumin in normal saline” NCT00798915 ↗ |
| Target | NTSR1 | “Xenin-25 (Xen) is a 25-amino acid neurotensin-related peptide that activates neurotensin receptor-1 (NTSR1).” PMID 24183983 ↗ Oct 2013 |