Drugs / Golvatinib
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 14 trials | ||||||
| Phase 1 | NCT01428141 | Sep 2011 → Jan 2013 | gastric cancer | Eisai Inc. | Completed | No outcome recorded |
| Phase 1 | NCT02533102 | Nov → Dec 2010 | — | Eisai Inc. | Completed | No outcome recorded |
| Phase 1 | NCT00921869 | Oct 2009 → Jun 2011 | cancer | Eisai Inc. | Completed | No outcome recorded |
| Phase 1 | NCT00869895 | Mar 2009 → Aug 2012 | cancer | Eisai Inc. | Completed | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT01355302 | Nov 2011 → Apr 2013 | — | Eisai Inc. | Terminated | No outcome recorded |
| Phase 1/2 | NCT01433991 | Oct 2011 → Mar 2015 | cancer | Eisai Inc. | Terminated | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/2 | NCT01332266 Comparator | Sep 2011 → Jan 2016 | head and neck squamous cell carcinoma | Eisai Inc. | Completed | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Golvatinib | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01433991 ↗ |
| Known as | E-7050 (GOLVATINIB) | ChEMBL registry synonym — accepted as the source's own label CHEMBL3039525 ↗ |
| Known as | E7050 | “This study is designed to first evaluate the effect of food on E7050's pharmacokinetic parameters following the administration of single 100 mg oral doses of E7050 tablet to...” NCT02533102 ↗ |
| Known as | ER-396901-08 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3039525 ↗ |
| Known as | GOLVATINIB (E7050) | ChEMBL registry synonym — accepted as the source's own label CHEMBL3039525 ↗ |
| Known as | GOLVATINIB TARTRATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL3039525 ↗ |
| Action | Inhibit | “Vascular endothelial growth factor receptor 2 inhibitor” CHEMBL3039525 ↗1“Hepatocyte growth factor receptor inhibitor” CHEMBL3039525 ↗ |
| Modality | Small molecule | — CHEMBL3039525 ↗ |
| Route | Oral | “given orally” NCT00869895 ↗ |
| Target | KDR | “Vascular endothelial growth factor receptor 2 inhibitor” CHEMBL3039525 ↗ |
| Target | MET | “Hepatocyte growth factor receptor inhibitor” CHEMBL3039525 ↗ |