drugset / Trial / NCT01332266

E7050 in Combination With Cetuximab Versus Cetuximab Alone in the Treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck

NCT01332266

Phase 1/2 Completed 95 enrolled Eisai Inc. PharmaBio Development Inc. · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether participants with platinum-resistant squamous cell carcinoma of the head and neck (SCCHN) who receive either E7050 administered with cetuximab or cetuximab alone experience greater benefit.

Timeline

Start
2011-09-19
Primary completion
2016-01-31
Completion
2017-09-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cetuximab Monoclonal antibody 250 mg/m2 Intravenous
Comparator Golvatinib Small molecule 200 mg Oral
Comparator Golvatinib Small molecule 300 mg Oral
Comparator Golvatinib Small molecule 400 mg Oral