drugset / Trial / NCT01332266
E7050 in Combination With Cetuximab Versus Cetuximab Alone in the Treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine whether participants with platinum-resistant squamous cell carcinoma of the head and neck (SCCHN) who receive either E7050 administered with cetuximab or cetuximab alone experience greater benefit.
Timeline
- Start
- 2011-09-19
- Primary completion
- 2016-01-31
- Completion
- 2017-09-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cetuximab | Monoclonal antibody | 250 mg/m2 | Intravenous |
| Comparator | Golvatinib | Small molecule | 200 mg | Oral |
| Comparator | Golvatinib | Small molecule | 300 mg | Oral |
| Comparator | Golvatinib | Small molecule | 400 mg | Oral |