Drugs / Cetuximab
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Cetuximab

Monoclonal antibody targets EGFR via inhibition

Developed for
colorectal cancer · head and neck squamous cell carcinoma · non-small cell lung carcinoma · head and neck cancer · cancer · esophageal cancer · oropharynx squamous cell carcinoma · gastric cancer
+181 more · malignant pancreatic neoplasm · metastasis from malignant tumor of colon · rectal cancer · hypopharynx squamous cell carcinoma · neoplasm · lung cancer · metastatic malignant neoplasm · metastatic neoplasm · squamous cell carcinoma · breast cancer · colorectal adenocarcinoma · colorectal carcinoma · nasopharyngeal carcinoma · pancreatic ductal adenocarcinoma · colorectal neoplasm · rectum adenocarcinoma · colon adenocarcinoma · colon carcinoma · metastatic squamous cell carcinoma · nasal cavity and paranasal sinus squamous cell carcinoma · nasopharyngeal squamous cell carcinoma · head and neck neoplasm · larynx verrucous carcinoma · cancer of unknown primary site · oral cavity squamous cell carcinoma · verrucous carcinoma of oral cavity · oropharyngeal carcinoma · skin squamous cell carcinoma · tongue cancer · esophageal squamous cell carcinoma · glioblastoma · laryngeal squamous cell carcinoma · oral cavity cancer · ovarian cancer · rectal carcinoma · cervical cancer · esophageal adenocarcinoma · malignant colon neoplasm · pancreatic adenocarcinoma · salivary gland squamous cell carcinoma · adenoid cystic carcinoma · anaplastic astrocytoma · hepatocellular carcinoma · larynx cancer · lung adenocarcinoma · anal carcinoma · cholangiocarcinoma · colon mucinous adenocarcinoma · colon signet ring cell adenocarcinoma · esthesioneuroblastoma · gallbladder cancer · high grade malignant neoplasm · hypopharynx cancer · inverted papilloma · laryngeal carcinoma · lung large cell carcinoma · lymphoepithelial-like carcinoma · nasal cavity and paranasal sinus lethal midline granuloma · oral cavity mucoepidermoid carcinoma · precancerous condition · renal cell carcinoma · salivary gland cancer · triple-negative breast carcinoma · adenosquamous lung carcinoma · brain cancer · breast carcinoma · carcinoma of lip · carcinoma of pharynx · cervical squamous cell carcinoma · chordoma · endometrial cancer · fibrillary astrocytoma · gastric adenocarcinoma · gastroesophageal junction adenocarcinoma · HER2 positive breast carcinoma · hypopharyngeal carcinoma · lip and oral cavity carcinoma · lip and oral cavity squamous cell carcinoma · liver cancer · metastatic malignant neoplasm in the colon · neoplastic disease or syndrome · non-small cell squamous lung carcinoma · oral cavity neoplasm · oropharynx cancer · pancreatic neoplasm · pharynx neoplasm · plasma cell myeloma · primary peritoneal carcinoma · rectal signet ring cell adenocarcinoma · rectum mucinous adenocarcinoma · sarcoma · urinary bladder cancer · urothelial carcinoma · acute myeloid leukemia, KRAS gene mutation · adenocarcinoma · adenosquamous carcinoma · anal canal cancer · anal squamous cell carcinoma · anaplastic oligoastrocytoma · anus cancer · appendix cancer · appendix carcinoma · basaloid carcinoma · basaloid squamous cell carcinoma · bile duct cancer · biliary tract cancer · breast neoplasm · carcinoid tumor · carcinoma · carcinoma of esophagus · Castleman disease · castration-resistant prostate carcinoma · cervical adenosquamous carcinoma · cervical carcinoma · cervical small cell carcinoma · colonic neoplasm · colorectal cancer, susceptibility to, 4 · complex regional pain syndrome · diffuse intrinsic pontine glioma · diffuse midline glioma, H3 K27M-mutant · endometrial carcinoma · Erdheim-Chester disease · extrahepatic bile duct carcinoma · fallopian tube neoplasm · female breast carcinoma · female reproductive system neoplasm · gallbladder adenocarcinoma · gastroesophageal adenocarcinoma · gastrointestinal stromal tumor · head and neck carcinoma · kidney cancer · laryngeal neoplasm · liver and intrahepatic bile duct neoplasm · lung carcinoma · lymphangioleiomyomatosis · major salivary gland carcinoma · male reproductive system neoplasm · malignant glioma · malignant tumor of neck · mesothelial neoplasm · metastatic melanoma · nasal cavity and paranasal sinus carcinoma · nasal cavity cancer · nasal cavity neoplasm · nasal cavity squamous cell carcinoma · neoplasm of esophagus · neuralgia · NF2-related schwannomatosis · oligoastrocytoma · oligodendroglioma · pancreas disorder · paranasal sinus cancer · paranasal sinus neoplasm · paranasal sinus squamous cell carcinoma · peritoneal neoplasm · pharynx cancer · pilomyxoid astrocytoma · prostate cancer · prostate carcinoma · rectal neoplasm · respiratory system cancer · respiratory tract neoplasm · skin basal cell carcinoma · skin neoplasm · small intestine adenocarcinoma · small intestine cancer · small intestine leiomyosarcoma · small intestine lymphoma · soft tissue sarcoma · squamous cell carcinoma of lip · squamous cell carcinoma of penis · squamous cell lung carcinoma · thymic carcinoma · thymoma · thyroid gland carcinoma · tongue carcinoma · undifferentiated carcinoma · undifferentiated carcinoma of nasopharynx · urothelial neoplasm · mucinous adenocarcinoma · refractory malignant neoplasm
Investigated by
National Cancer Institute (NCI) · Bristol-Myers Squibb · Eli Lilly and Company · Merck Sharp & Dohme LLC · Merck KGaA, Darmstadt, Germany · M.D. Anderson Cancer Center
+523 more · Fudan University · Pfizer · Sanofi · Memorial Sloan Kettering Cancer Center · Dana-Farber Cancer Institute · Sun Yat-sen University · Alliance for Clinical Trials in Oncology · Celgene Corporation · Eastern Cooperative Oncology Group · Washington University School of Medicine · Merck Serono International SA · SWOG Cancer Research Network · Gruppo Oncologico del Nord-Ovest · Hoffmann-La Roche · UNC Lineberger Comprehensive Cancer Center · UNICANCER · Gustave Roussy, Cancer Campus, Grand Paris · ImmunityBio, Inc. · NRG Oncology · Novartis Pharmaceuticals · University of Chicago · AstraZeneca · Beth Israel Deaconess Medical Center · Boehringer Ingelheim · Brigham and Women's Hospital · Groupe Oncologie Radiotherapie Tete et Cou · Massachusetts General Hospital · Radiation Therapy Oncology Group · Second Affiliated Hospital, School of Medicine, Zhejiang University · Fate Therapeutics · Federation Francophone de Cancerologie Digestive · Fox Chase Cancer Center · Roche Pharma AG · Ruijin Hospital · Shanghai Zhongshan Hospital · Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) · University of Michigan Rogel Cancer Center · GERCOR - Multidisciplinary Oncology Cooperative Group · Georgetown University · Gynecologic Oncology Group · Heidelberg University · Jiangsu Cancer Institute & Hospital · NSABP Foundation Inc · Northwell Health · Odense University Hospital · Regeneron Pharmaceuticals · RenJi Hospital · Shanghai Jiao Tong University School of Medicine · Spanish Head And Neck Cancer Cooperative Group · Swiss Cancer Institute · US Oncology Research · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · University Hospital of Crete · University of Campania Luigi Vanvitelli · University of Colorado, Denver · University of Pittsburgh · University of Wisconsin, Madison · AIO-Studien-gGmbH · Bayer · Cancer and Leukemia Group B · Chang Gung Memorial Hospital · City Clinical Oncology Hospital No 1 · Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · European Organisation for Research and Treatment of Cancer - EORTC · Fujian Cancer Hospital · Genentech, Inc. · Genfleet Therapeutics (Shanghai) Inc. · Gilead Sciences · H. Lee Moffitt Cancer Center and Research Institute · Institute of Oncology Ljubljana · Merck, S.L., Spain · Moscow Multidisciplinary Clinical Center "Kommunarka" · NCIC Clinical Trials Group · all 529 on the full record

Regulatory milestones approvals, filings & regulatory actions · 8 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (6) US (FDA) ERBITUX — 2006-03-01 – 2021-09-24 fda.gov ↗
Approved EU (EMA) Erbitux — 2004-06-29 europa.eu ↗
Approved US (FDA) ERBITUX — 2004-02-12 fda.gov ↗

Trials 776 · started per year

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 04 trials
Phase 0 NCT05816785 Apr 2023 → Aug 2026 head and neck squamous cell carcinoma University of Wisconsin, Madison Completed No outcome recorded
Phase 0 NCT04065555 Oct 2020 → Jun 2022 head and neck cancer Presage Biosciences Completed No outcome recorded
Phase 0 NCT00835679 Dec 2009 → Feb 2011 colon mucinous adenocarcinoma, colon signet ring cell adenocarcinoma, metastasis from malignant tumor of colon, rectal signet ring cell adenocarcinoma +1 National Cancer Institute (NCI) Terminated No outcome recorded
Phase 0 NCT00757549 Sep 2008 → Aug 2011 head and neck cancer Mayo Clinic Completed No outcome recorded
Phase 1130 trials · 1 met primary
Phase 1 NCT07746141 Sep 2026 → Sep 2028 expected metastatic malignant neoplasm BeOne Medicines Recruiting No outcome recorded
Phase 1 NCT07543471 Jun 2026 → Jun 2027 expected colorectal cancer Shanghai Henlius Biotech Not yet recruiting No outcome recorded
Phase 1 NCT07535112 Apr 2026 → Jul 2029 expected colorectal adenocarcinoma Bayer Recruiting No outcome recorded
Phase 1 NCT07349537 Jan 2026 → Apr 2028 expected colorectal cancer, non-small cell lung carcinoma, pancreatic ductal adenocarcinoma Revolution Medicines, Inc. Recruiting No outcome recorded
Phase 1 NCT07247110 Dec 2025 → Dec 2030 expected cancer Merck Sharp & Dohme LLC Recruiting No outcome recorded
Phase 1 NCT07216105 Nov 2025 → Jan 2028 expected breast cancer, colorectal cancer, endometrial carcinoma, head and neck squamous cell carcinoma +2 Fate Therapeutics Recruiting No outcome recorded
Phase 1 NCT06806852 May 2025 → Aug 2027 expected head and neck squamous cell carcinoma Boehringer Ingelheim Active not recruiting No outcome recorded
Phase 1 NCT06917079 Mar 2025 → Aug 2027 expected colorectal cancer, non-small cell lung carcinoma, pancreatic ductal adenocarcinoma TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) Recruiting No outcome recorded
Phase 1 NCT06764771 Mar 2025 → Oct 2027 expected cancer Bristol-Myers Squibb Recruiting No outcome recorded
Phase 1 NCT06835569 Mar 2025 → May 2029 expected colorectal cancer, non-small cell lung carcinoma, pancreatic ductal adenocarcinoma Alterome Therapeutics, Inc. Recruiting No outcome recorded
Show all 130 trials opens the full record — a long page
Phase 1/2101 trials · 3 missed
Phase 1/2 NCT07863869 Sep 2026 → May 2029 expected colorectal cancer Cancer Institute and Hospital, Chinese Academy of Medical Sciences Not yet recruiting No outcome recorded
Phase 1/2 NCT07468071 Jun 2026 → Jun 2029 expected — Novartis Pharmaceuticals Active not recruiting No outcome recorded
Phase 1/2 NCT07286149 Apr 2026 → Aug 2029 expected lung cancer Merck Sharp & Dohme LLC Recruiting No outcome recorded
Phase 1/2 NCT07397338 Jan 2026 → May 2029 expected colorectal cancer, metastatic neoplasm, non-small cell lung carcinoma Revolution Medicines, Inc. Recruiting No outcome recorded
Phase 1/2 NCT07223047 Nov 2025 → Oct 2028 expected colorectal cancer, high grade malignant neoplasm, non-small cell lung carcinoma, pancreatic ductal adenocarcinoma Bristol-Myers Squibb Recruiting No outcome recorded
Phase 1/2 NCT07259590 Oct 2025 → Jul 2027 expected colorectal cancer, pancreatic ductal adenocarcinoma Genfleet Therapeutics (Shanghai) Inc. Recruiting No outcome recorded
Phase 1/2 NCT07059221 Jul 2025 → Mar 2027 expected head and neck squamous cell carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT05956821 Jun 2025 → Oct 2029 expected anaplastic astrocytoma, diffuse midline glioma, H3 K27M-mutant, fibrillary astrocytoma, glioblastoma +1 University of Miami Recruiting No outcome recorded
Phase 1/2 NCT07012954 Jun 2025 → Dec 2027 expected colorectal cancer Sun Yat-sen University Recruiting No outcome recorded
Phase 1/2 NCT06943820 May 2025 → Dec 2026 expected colorectal adenocarcinoma, head and neck squamous cell carcinoma, non-small cell lung carcinoma Akeso Recruiting No outcome recorded
Phase 2432 trials · 16 met primary · 30 missed
Phase 2 NCT06418724 Oct 2026 → Jul 2030 expected skin squamous cell carcinoma Melanoma and Skin Cancer Trials Limited Not yet recruiting No outcome recorded
Phase 2 NCT07814417 Oct 2026 → Nov 2028 expected colorectal neoplasm Eli Lilly and Company Not yet recruiting No outcome recorded
Phase 2 NCT07815288 Sep 2026 → Dec 2029 expected colorectal adenocarcinoma Peking University Cancer Hospital & Institute Not yet recruiting No outcome recorded
Phase 2 NCT07659795 Jul 2026 → Jun 2027 expected colorectal cancer Verastem, Inc. Recruiting No outcome recorded
Phase 2 NCT07644559 Jun 2026 → Jun 2027 expected pancreatic ductal adenocarcinoma Verastem, Inc. Recruiting No outcome recorded
Phase 2 NCT07490119 Jun 2026 → Jun 2028 expected colorectal cancer, susceptibility to, 4 Fudan University Not yet recruiting No outcome recorded
Phase 2 NCT07515963 Jun 2026 → Feb 2027 expected colorectal cancer Zhongnan Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07621497 Jun 2026 → Jun 2029 expected metastatic malignant neoplasm in the colon Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 2 NCT07554859 May 2026 → Apr 2027 expected non-small cell lung carcinoma Genfleet Therapeutics (Shanghai) Inc. Not yet recruiting No outcome recorded
Phase 2 NCT07581626 May 2026 → Apr 2027 expected rectal cancer Chinese PLA General Hospital Not yet recruiting No outcome recorded
Show all 432 trials opens the full record — a long page
Phase 2/311 trials · 1 met primary · 1 missed
Phase 2/3 NCT05710406 Aug 2023 → Jun 2034 expected colon adenocarcinoma Alliance for Clinical Trials in Oncology Active not recruiting No outcome recorded
Phase 2/3 NCT05063552 Mar 2023 → Dec 2027 expected hypopharynx squamous cell carcinoma, laryngeal squamous cell carcinoma, lip and oral cavity squamous cell carcinoma, nasal cavity and paranasal sinus squamous cell carcinoma +5 National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 2/3 NCT05409417 Oct 2022 → Feb 2024 metastasis from malignant tumor of colon Second Affiliated Hospital, School of Medicine, Zhejiang University Unknown No outcome recorded
Phase 2/3 NCT02942706 Nov 2021 → Oct 2022 colorectal cancer Ruijin Hospital Unknown No outcome recorded
Phase 2/3 NCT02978313 Nov 2016 → Nov 2019 colorectal cancer Ruijin Hospital Unknown No outcome recorded
Phase 2/3 NCT02438722 May 2015 → Sep 2018 non-small cell lung carcinoma SWOG Cancer Research Network Completed Missed primary
Phase 2/3 NCT01810913 Mar 2013 → Jan 2027 hypopharynx squamous cell carcinoma, laryngeal squamous cell carcinoma, oral cavity squamous cell carcinoma, oropharynx squamous cell carcinoma National Cancer Institute (NCI) Suspended No outcome recorded Stop: Enrollment
Phase 2/3 NCT01434394 Aug 2011 → Oct 2014 chemotherapy-induced toxicity, oral cavity cancer, oropharyngeal carcinoma Shanghai Jiao Tong University School of Medicine Completed No outcome recorded
Phase 2/3 NCT00975897 Jul 2009 → Aug 2010 colorectal cancer Medical Research Council Completed No outcome recorded
Phase 2/3 NCT01550055 May 2009 → Dec 2012 colorectal cancer Shanghai Zhangjiang Biotechnology Limited Company Completed Met primary
Phase 374 trials · 8 met primary · 19 missed
Phase 3 NCT07441681 Jan 2027 → Nov 2035 expected head and neck squamous cell carcinoma, hypopharyngeal carcinoma, lip and oral cavity carcinoma, oropharyngeal carcinoma NRG Oncology Not yet recruiting No outcome recorded
Phase 3 NCT07509099 Sep 2026 → Sep 2031 expected head and neck squamous cell carcinoma Ji Dongmei Recruiting No outcome recorded
Phase 3 NCT07549399 May 2026 → Apr 2029 expected rectum adenocarcinoma Sixth Affiliated Hospital, Sun Yat-sen University Recruiting No outcome recorded
Phase 3 NCT07432087 Feb 2026 → Dec 2030 expected head and neck squamous cell carcinoma Yue He, MD Not yet recruiting No outcome recorded
Phase 3 NCT07004413 Jan 2026 → Jan 2028 expected colorectal cancer Charite University, Berlin, Germany Not yet recruiting No outcome recorded
Phase 3 NCT07389265 Oct 2025 → Oct 2030 expected colorectal cancer University of Campania Luigi Vanvitelli Recruiting No outcome recorded
Phase 3 NCT06998069 Aug 2025 → Jun 2026 overdue head and neck squamous cell carcinoma Brown University Recruiting No outcome recorded
Phase 3 NCT06997497 Jul 2025 → Mar 2029 expected colon adenocarcinoma, rectum adenocarcinoma Merck Sharp & Dohme LLC Recruiting No outcome recorded
Phase 3 NCT06589804 Mar 2025 → Nov 2029 expected hypopharynx squamous cell carcinoma, laryngeal squamous cell carcinoma, oral cavity squamous cell carcinoma, oropharynx squamous cell carcinoma National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 3 NCT06647563 Nov 2024 → Sep 2029 expected head and neck squamous cell carcinoma Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University Not yet recruiting No outcome recorded
Phase 45 trials · 1 met primary
Phase 4 NCT07094893 Apr 2026 → Mar 2028 expected colorectal cancer Gruppo Oncologico del Nord-Ovest Not yet recruiting No outcome recorded
Phase 4 NCT05203172 Jul 2022 → Jul 2029 expected cancer Pfizer Recruiting No outcome recorded
Phase 4 NCT01315990 Jan 2011 → Mar 2015 colorectal cancer Dr. Carl Schimanski Unknown No outcome recorded
Phase 4 NCT01564810 Sep 2006 → Jun 2012 colorectal adenocarcinoma, metastatic malignant neoplasm Xu jianmin Unknown Met primary
Phase 4 NCT00327093 May 2006 → Oct 2008 colorectal cancer, metastatic neoplasm Hospices Civils de Lyon Terminated No outcome recorded
Phase not applicable19 trials
— NCT06199232 Jan 2024 → Jun 2026 overdue metastasis from malignant tumor of colon Peking University Active not recruiting No outcome recorded
— NCT06035133 Nov 2023 → Nov 2024 overdue rectal cancer Tang-Du Hospital Not yet recruiting No outcome recorded
— NCT05963087 Aug 2023 → Feb 2025 colorectal cancer Zhejiang Cancer Hospital Unknown No outcome recorded
— NCT05873972 Jun 2023 → Jun 2024 metastasis from malignant tumor of colon Fudan University Unknown No outcome recorded
— NCT05978349 Feb 2022 → Sep 2025 colorectal cancer Peking Union Medical College Hospital Unknown No outcome recorded
— NCT05424692 Sep 2021 → Sep 2025 overdue chemotherapy-induced toxicity, colon carcinoma, rectal carcinoma Peking Union Medical College Hospital Recruiting No outcome recorded
— NCT02177838 Mar 2015 → Aug 2019 hypopharynx squamous cell carcinoma, larynx verrucous carcinoma, oropharynx squamous cell carcinoma, tongue cancer Rutgers, The State University of New Jersey Terminated No outcome recorded Stop: Enrollment
— NCT02324608 Jan 2015 → Dec 2020 skin squamous cell carcinoma Rutgers, The State University of New Jersey Completed No outcome recorded
— NCT02241187 Sep 2014 → Sep 2016 pancreatic adenocarcinoma Memorial Sloan Kettering Cancer Center Completed No outcome recorded
— NCT01631539 Sep 2012 → Dec 2014 metastasis from malignant tumor of colon Universitaire Ziekenhuizen KU Leuven Withdrawn No outcome recorded Stop: Enrollment
Comparator or background therapy255 trials
Phase 0 NCT07318389 Background Jun 2026 → Nov 2027 expected colorectal cancer M.D. Anderson Cancer Center Not yet recruiting No outcome recorded
Phase 0 NCT06011772 Background Dec 2023 → Feb 2026 overdue colorectal cancer Roswell Park Cancer Institute Active not recruiting No outcome recorded
Phase 1 NCT07672483 Background Oct 2026 → Jan 2028 expected cancer or benign tumor National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 1 NCT07813468 Comparator Sep 2026 → Jun 2027 expected — HC Biopharma Inc. Recruiting No outcome recorded
Phase 1 NCT07217028 Background Apr 2026 → Apr 2029 expected head and neck squamous cell carcinoma Vanderbilt-Ingram Cancer Center Recruiting No outcome recorded
Show all 255 trials opens the full record — a long page

Press releases naming this drug 61 releases

DateIssuerRelease
2026-09-30 Hummingbird Bioscience Hummingbird Bioscience Announces First Patient Dosed in Phase II Trial of HMBD-001 and Cetuximab in Advanced Squamous Cell Cancers hummingbirdbioscience.com ↗
2026-07-14 Merck KGaA, Darmstadt, Germany European Commission Approves Erbitux® (cetuximab) in Combination with Encorafenib and FOLFOX for First-Line Treatment of Metastatic Colorectal Cancer with BRAF V600E Mutation emdgroup.com ↗
2026-07-08 Shanghai Henlius Biotech First Patient Dosed in China for Phase 1 Clinical Trial of Henlius’ Cetuximab Biosimilar HLX05-N henlius.com ↗
2026-05-10 Shanghai Henlius Biotech Globalisation 2.0 | U.S. FDA Clearance of IND for Cetuximab Biosimilar HLX05-N henlius.com ↗
2026-04-14 Shanghai Henlius Biotech NMPA Grants IND Approval for Henlius' Cetuximab Biosimilar HLX05-N henlius.com ↗
2025-02-07 Klus Pharma Inc. Kelun-Biotech’s Product Cetuximab N01 Injection Approved For Marketing By NMPA Of China kluspharma.com ↗
2024-10-29 Biond Biologics Biond Biologics Announces Clinical Trial Collaboration and Supply Agreement with Merck KGaA, Darmstadt, Germany to Evaluate BND-35 in Combination with Cetuximab in a Phase 1 Clinical Study biondbio.com ↗
2024-06-26 Jiangsu Simcere Pharmaceutical Co., Ltd. Simcere Zaiming Announce Approval of Cetuximab Beta in China by the NMPA simcere.com ↗
2024-06-21 Bristol-Myers Squibb Bristol Myers Squibb Announces U.S. FDA Accelerated Approval of KRAZATI® (adagrasib) in Combination with Cetuximab for Adult Patients with Previously Treated KRAS G12C-Mutated Locally Advanced or Metastatic Colorectal Cancer (CRC) bms.com ↗
2024-04-08 Bristol-Myers Squibb KRAZATI (adagrasib) in Combination with Cetuximab Demonstrates Clinically Meaningful Activity as a Targeted Treatment Option for Patients with Previously Treated KRAS G12C-Mutated Locally Advanced or Metastatic Colorectal Cancer (CRC) bms.com ↗
2024-02-27 Purple Biotech Ltd. Purple Biotech Presents Data of its Phase 1 Head & Neck Cancer of NT219 in combination with Cetuximab at ESMO TAT Congress 2024 purple-biotech.com ↗
2024-02-20 Bristol-Myers Squibb U.S. Food and Drug Administration (FDA) Accepts Supplemental New Drug Application for KRAZATI® (adagrasib) in Combination with Cetuximab as a Targeted Treatment Option for Patients with Previously Treated KRAS G12C-Mutated Locally Advanced or... bms.com ↗

Evidence & citations 23 cited values

Every value below carries the sentence it was read from. 1,039 sources stand behind the page.

FieldValueCited text
Known as Cetuximab “Investigator's choice of standard first-line systemic therapy for initially unresectable colorectal cancer, including chemotherapy (e.g., FOLFOX, FOLFIRI, CAPOX) with or...” NCT07509398 ↗
1015

“Choose chemotherapeutic drugs(5-fluorouracil + formyltetrahydrofolate/Oxaliplatin + 5-fluorouracil + formyltetrahydrofolate/Irinotecan + 5-fluorouracil +...” NCT05978349 ↗

“Tivantinib 360 mg twice daily in combination with other anti-cancer therapy (eg, erlotinib,sorafenib, pemetrexed, docataxel, gemcitabine, irinotecan, and/or cetuximab) at the...” NCT01178411 ↗

“During cycle I (chemoradiation), gemcitabine (200 mg/m2) and cetuximab 400mg/m2 initial dose followed by 250mg/m2 IV weekly will be given with continuous infusion 5-FU (200...” NCT00424827 ↗

“The acceptable weekly chemotherapy regimens are Cisplatin 30 to 40 mg/m2 (first choice), Cetuximab 250mg/m2 (second choice), Carboplatin AUC 1.5 and paclitaxel 45 mg/m2 (third...” NCT03077243 ↗

“Eligible subjects will be treated with tivantinib (ARQ 197) at a dose of 360 mg twice daily (a total daily dose of 720 mg) orally in a continuous manner and cetuximab (Erbitux)...” NCT01892527 ↗

“A Randomized, Single Intravenous Dose, Parallel Phase I Clinical Study to Compare the Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX05 Vs. Erbitux®...” NCT06980454 ↗

“Drug: cetuximab 400 mg/m2 for the first dose, then 250 mg/sqm, intravenous infusion, repeated weekly; or Cetuximab 500 mg/ sqm, intravenous infusion, D1, repeated every 2 weeks.” NCT05652894 ↗

“Cetuximab 400mg/m2 will be used one week before radiotherapy and 250mg/m2/week during IMRT, or nimotuzumab 200mg/week; meanwhile, cisplatin 80mg/m2 will be used every 3 weeks.” NCT04508829 ↗

“First-line standard systemic therapies in cohort A include: FOLFOX/FOLIRI/XELOX+ bevacizumab, FOLFOX/FOLIRI/XELOX+cetuximab (KRAS/NRAS/BRAF WT and left-sided tumors only).” NCT06841159 ↗

“* Cetuximab (only for patients with K-ras wild type and positive EGFR mutation) 400 mg/m2 IV over 2 hrs on Day 1, and 250 mg/m2 IV over 1 hr on Day 8, 15, 22, 29, and 36.” NCT01923987 ↗

Show 1,005 more sources

Known as C-225 “A Phase III Randomized Study of Cetuximab (Erbitux™, C225) and Best Supportive Care Versus Best Supportive Care in Patients With Pretreated Metastatic Epidermal Growth Factor...” NCT00079066 ↗
16

“A Phase II Study Of Oxaliplatin (OXAL), 5-Fluorouracil (5-FU), Leucovorin (CF), and Cetuximab (C225) For Patients With Unresectable Hepatic Metastases From Metastatic...” NCT00056030 ↗

“A Phase II Trial of Cetuximab (c225) as Therapy for Recurrent Non-Small Cell Lung Cancer in Patients Who Have Received Prior Therapy With Tyrosine Kinase Inhibitor Directed...” NCT00694603 ↗

“Cetuximab (C225) and Radiation in Elderly and /or Poor Performance Status Patients With Locally Advanced Non-Small Cell Lung Cancer: A Phase II Study to Evaluate Survival and Toxicity” NCT00124618 ↗

“This is an open, multicenter phase Ⅱ clinical trial on cetuximab (C225) combined with IMRT + concurrent chemotherapy of cisplatin in locoregionally advanced nasopharyngeal carcinoma.” NCT00700440 ↗

“A Phase I Trial of Tailored Radiation Therapy With Concomitant Cetuximab (C225, NSC #714692) and Cisplatin (NSC #119875) in the Treatment of Patients With Cervical Cancer” NCT00104910 ↗

“C225 = Cetuximab: 400 mg/m2 IV will be given as the initial OR loading dose in week 1 and then 250 mg/m2 IV weekly will be given for 8 weeks (weeks 2-9).” NCT00343083 ↗

“Cetuximab (C-225), a Chimeric Monoclonal Antibody Against the Epidermal Growth Factor Receptor (EGFR)” NCT00820417 ↗

“Cetuximab (C225) is a human/murine chimeric monoclonal antibody directed to the EGFR binding site.” NCT00536614 ↗

“cetuximab (C225), an antibody that inhibits epidermal growth factor receptor (EGFR) activity” PMID 21329967 ↗ Feb 2011

“Pre-RT cetuximab (C225), 400 mg/m²IV and weekly C225, 250 mg/m2 IV in during RT.” NCT01758731 ↗

Show 6 more sources

Known as Cetux “The BEACON CRC study demonstrated that encorafenib (Enco)+cetuximab (Cetux)±binimetinib (Bini) significantly improved overall survival (OS) versus” PMID 39313594 ↗ Sep 2024
Known as cetuxiamb “EGFR antibodies panitumumad and cetuxiamb in case of KRAS wild-type tumors.” NCT02314182 ↗
Known as Cetuximab (C225, Erbitux by Merck) “Cetuximab (C225, Erbitux by Merck)” NCT00422773 ↗
Known as Cetuximab (C225, Erbitux) “Cetuximab (C225, Erbitux)” NCT00580073 ↗
Known as Cetuximab (Erbitux) “Cetuximab (Erbitux)” NCT01192087 ↗
2

“Cetuximab (Erbitux)” NCT01181401 ↗

“Cetuximab (Erbitux)” NCT01309126 ↗

Known as Cetuximab Beta “Camrelizumab 200 mg (Day 1) intravenous infusion (IV), Cetuximab Beta 400 mg/m² (Day 1) IV, followed by 250 mg/m² IV weekly, with a 21-day cycle for 2 cycles; followed by...” NCT07432087 ↗
Known as Cetuximab Beta Injection “Cetuximab Beta Injection 500mg/㎡ IV, q14d” NCT07294261 ↗
Known as Cetuximab or c225 “Cetuximab or c225” NCT05959356 ↗
Known as cetuximab β “Despite this established approach, cetuximab β (CMAB009), as a modified antibody of cetuximab, prospectively selected for dual RAS/BRAF wild-type patients, has not yet been...” PMID 40328753 ↗ May 2025
Known as Cetuximab(C225, Erbitux, Merck KGaA) “Cetuximab(C225, Erbitux®, Merck KGaA)” NCT00153998 ↗
Known as CMAB009 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03206151 ↗
1

NCT01550055 ↗

Known as CTX “GBM often has a high expression EFGR (Epidermal Growth Factor Receptor) which is blocked by Cetuximab (CTX).” NCT02861898 ↗
3

“an epidermal growth factor receptor inhibitor cetuximab (CTX) added to the concurrent therapy” NCT00343083 ↗

“intracranial superselective intra-arterial infusion of Cetuximab (CTX), at a dose of 250mg/m2” NCT02800486 ↗

“cetuximab (CTX) or nimotuzumab (NTZ)” NCT04508816 ↗

Known as Erbitux “the rationale of the combination of lenalidomide with a therapeutic IgG1 antibody such as cetuximab (Erbitux®) is based on the fact that several reports suggest a role of...” NCT01166035 ↗
58

“A Phase Ib Open-label Clinical Trial of Continuous Once Daily Oral Treatment Using BIBW 2992 Plus Cetuximab (Erbitux®) in Patients With Non-small cell Lung Cancer With...” NCT01090011 ↗

“A Phase III Randomized Study of Cetuximab (Erbitux™, C225) and Best Supportive Care Versus Best Supportive Care in Patients With Pretreated Metastatic Epidermal Growth Factor...” NCT00079066 ↗

“Eligible subjects will be treated with tivantinib (ARQ 197) at a dose of 360 mg twice daily (a total daily dose of 720 mg) orally in a continuous manner and cetuximab (Erbitux)...” NCT01892527 ↗

“Cetuximab (ErbituxTM) is designed to prevent or slow down the growth of cancer cells by blocking proteins inside the cancer cell, called the epidermal growth factor receptor (EGFR).” NCT00543504 ↗

“The purpose of this study is to investigate whether cetuximab (Erbitux®) with cisplatin and capecitabine (Xeloda) as 1st line treatment in the advanced gastric cancer is effective.” NCT00477711 ↗

“Cetuximab (Erbitux®) is a recombinant chimeric human/mouse Immunoglobulin G monoclonal antibody which binds to EGFR and competitively inhibits the binding of EGFR and other ligands” NCT06599502 ↗

“A Phase I-IIa Dose-Ranging Study of Pemetrexed (Alimta) Plus Cetuximab (Erbitux) in Patients With Recurrent Non-Small Cell Lung Cancer (NSCLC): Hoosier Oncology Group LUN04-79” NCT00216203 ↗

“The initial dose of cetuximab (ERBITUX) is 400 mg/m² intravenously administered over 120 minutes, followed by 11 weekly infusions at 250 mg/m² IV over 60 minutes” NCT01102231 ↗

“Erbitux: 400 mg/m2 as a loading dose one week prior to radiation and taxotere, and then at 250 mg/m2 given weekly on Day 1 of treatment week following Taxotere.” NCT01794845 ↗

“Cetuximab (Erbitux® )- Cetuximab is a recombinant IgG1 chimeric monoclonal antibody directed against human epidermal growth factor receptor (EGFR).” NCT01315990 ↗

Show 48 more sources

Known as ERBITUX (cetuximab) “ERBITUX (cetuximab)” NCT00517829 ↗
1

“Erbitux (cetuximab)” NCT00931840 ↗

Known as ErbituxÒ “Cetuximab (ErbituxÒ) (Arm B only) every two weeks:” NCT00552149 ↗
Known as IMC-C225 “Comparing Gemcitabine Plus Cetuximab (IMC-C225) Versus Gemcitabine” NCT00075686 ↗
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“IMC-C225” NCT00980239 ↗

Known as NSC #714692 “A Phase I Trial of Tailored Radiation Therapy With Concomitant Cetuximab (C225, NSC #714692) and Cisplatin (NSC #119875) in the Treatment of Patients With Cervical Cancer” NCT00104910 ↗
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“cetuximab (C225, NSC #714692) in Combination With Carboplatin (NSC #241240)” NCT00086892 ↗

Action Inhibit “the monoclonal antibody EGFR inhibitor, cetuximab” PMID 16246975 ↗ Oct 2005
Modality Monoclonal antibody “We conducted a multinational, randomized study to compare radiotherapy alone with radiotherapy plus cetuximab, a monoclonal antibody against the epidermal growth factor...” PMID 16467544 ↗ Feb 2006
Route Intravenous “Patients receive maintenance cetuximab IV over 1 hour on day 8.” NCT00004227 ↗
Target EGFR “Phase II Study of Cetuximab Anti-Epidermal Growth Factor Receptor (EGFr) Antibody” NCT00004865 ↗