drugset / Trial / NCT07300150

A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors

NCT07300150

Phase 1 Recruiting 210 enrolled PAQ Therapeutics, Inc.
RandomizedSequentialOpen-labelTreatment

Summary

The primary purpose of this study is to evaluate the safety and tolerability, determine the maximally tolerated dose (MTD) and/or recommended Phase 2 dose(s) (RP2D) of PT0511 in adult participants with solid tumors as monotherapy and in combination with cetuximab in participants with colorectal cancer (CRC).

Timeline

Start
2025-11-21
Primary completion
2028-10-18
Completion
2028-10-18

Drugs

EvaluationDrugModalityDoseRoute
Subject PT0511 Unknown Intravenous
Background Cetuximab Monoclonal antibody Intravenous