drugset / Trial / NCT06764771

A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors

NCT06764771

Phase 1 Recruiting 437 enrolled Bristol-Myers Squibb
Non-randomizedSequentialOpen-labelTreatment

Summary

This purpose of this study is to determine if experimental treatment with BMS-986488, alone, or in combinations is safe, tolerable, and has anti-cancer activity in patients with advanced malignant tumors.

Timeline

Start
2025-03-25
Primary completion
2027-10-15
Completion
2027-10-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Adagrasib Small molecule
Subject BMS-986488 Unknown
Subject Cetuximab Monoclonal antibody
Subject Nivolumab Monoclonal antibody

Indications