drugset / Trial / NCT07468071

Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

NCT07468071

Phase 1/2 Recruiting 40 enrolled Novartis Pharmaceuticals
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to allow continued access to opnurasib (JDQ443) to participants who are benefitting from treatment with opnurasib as a single agent or in combination with other study treatments in pre-defined Novartis-sponsored opnurasib studies and to continue to assess safety in these participants.

Timeline

Start
2026-06-08
Primary completion
2029-06-15
Completion
2029-09-17

Drugs

EvaluationDrugModalityDoseRoute
Subject BATOPROTAFIB Small molecule
Subject Cetuximab Monoclonal antibody
Subject Opnurasib Small molecule
Subject Tislelizumab Monoclonal antibody
Subject Trametinib Small molecule

Indications

No indication recorded.