drugset / Trial / NCT06179160

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

NCT06179160

Phase 1 Recruiting 710 enrolled Incyte Corporation
Non-randomizedSequentialOpen-labelTreatment

Summary

This study is conducted to determine the safety and tolerability of INCB161734 as a single agent or in combination with other anticancer therapies.

Timeline

Start
2024-01-04
Primary completion
2027-01-01
Completion
2027-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject INCB161734 Unknown
Background Cetuximab Monoclonal antibody
Background GEMNabP Unknown
Background INCA33890 Unknown
Background Oxaliplatin Small molecule
Background Retifanlimab Monoclonal antibody
Background fluorouracil Small molecule
Background mFOLFIRINOX Unknown

Indications