Drugs / INCA33890
last change Mar 2026 re-read 9 days ago

INCA33890

Developed for
colorectal cancer · cancer · metastatic neoplasm
Investigated by
Incyte Corporation

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05836324 Jul 2023 → Jan 2027 expected cancer, metastatic neoplasm Incyte Corporation Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT07823322 Oct 2026 → May 2029 expected colorectal cancer Incyte Corporation Not yet recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT07284849 Mar 2026 → Dec 2028 expected colorectal cancer Incyte Corporation Recruiting No outcome recorded
Comparator or background therapy1 trial
Phase 1 NCT06179160 Background Jan 2024 → Jan 2027 expected cancer Incyte Corporation Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2025-10-19 Incyte Corporation Results Incyte Announces Phase 1 Results for its TGFβR2×PD-1 Bispecific Antibody in Advanced Colorectal Cancer and KRAS G12D Inhibitor in Advanced Pancreatic Ductal Adenocarcinoma incyte.com ↗
Data presented at ESMO 2025 show INCA33890, a TGFβR2×PD-1 bispecific antibody, has the potential to be an effective treatment in microsatellite stable (MSS) colorectal cancer
2025-04-25 Incyte Corporation Results Incyte to Highlight Early-Stage Oncology Data at American Association for Cancer Research Annual Meeting 2025 incyte.com ↗
INCA33890, a Bispecific Antibody Targeting PD-1 and TGFβR2, Shows Enhanced Immune Responses in Models of Ovarian Cancer

Evidence & citations 1 cited value

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as INCA33890 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07284849 ↗
3

NCT07823322 ↗

NCT05836324 ↗

NCT06179160 ↗