drugset / Trial / NCT07644559

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

NCT07644559

Phase 2 Recruiting 180 enrolled Verastem, Inc.
RandomizedCrossoverSingle-blindTreatment

Summary

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic Cancer

Timeline

Start
2026-06-16
Primary completion
2027-06
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cetuximab Monoclonal antibody Subcutaneous
Subject VS-7375 Small molecule Oral