drugset / Trial / NCT00908024

Combination Study of BMS-754807 and Erbitux® in Subjects With Advanced or Metastatic Solid Tumors

NCT00908024

Phase 1/2 Terminated 54 enrolled Bristol-Myers Squibb
NaSingle-groupOpen-labelTreatment

Summary

The study is expected to identify a safe dose of BMS-754807 to be given in combination with a standard dose of cetuximab and the recommended dose or dose range for Phase II studies. The study is also intended to collect first data on the effects of the combination of BMS-754807 with cetuximab on tumors of patients with colorectal cancer or squamous cell cancer of the head and neck for whom cetuximab-containing therapies have not been effective

Timeline

Start
2009-10
Primary completion
2012-12
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Subject BMS-754807 Small molecule Oral
Background Cetuximab Monoclonal antibody 250 mg/m2 Intravenous