Drugs / BMS-754807
last change Nov 2014 re-read 2 minutes ago

BMS-754807

also known as BMS-754807-01

Small molecule targets IGF1R, INSR via inhibition

Developed for
metastatic neoplasm · breast cancer · neoplasm · cancer · colorectal cancer · head and neck cancer
Investigated by
Bristol-Myers Squibb · Mayo Clinic

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT01525823 Feb → Apr 2012 Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT00898716 Sep 2009 → Jul 2011 neoplasm Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT00793897 Apr 2009 → Jun 2012 cancer, metastatic neoplasm Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT00569036 Apr 2008 → Apr 2013 metastatic neoplasm, neoplasm Bristol-Myers Squibb Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT00908024 Oct 2009 → Dec 2012 colorectal cancer, head and neck cancer, metastatic neoplasm Bristol-Myers Squibb Terminated No outcome recorded
Phase 1/2 NCT00788333 Jul 2009 → Nov 2011 breast cancer Bristol-Myers Squibb Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01225172 Dec 2010 → Nov 2014 breast cancer Bristol-Myers Squibb Terminated No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as BMS-754807 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00898716
6

NCT00908024

NCT00793897

NCT01525823

NCT01225172

NCT00569036

NCT00788333

Known as BMS-754807-01 ChEMBL registry synonym — accepted as the source's own label CHEMBL575448
Action Inhibit “Insulin-like growth factor I receptor inhibitor” CHEMBL575448
2

“BMS-754807 (IGR-IR/IR Inhibitor)” NCT01525823

“Insulin receptor inhibitor” CHEMBL575448

Modality Small molecule CHEMBL575448
Route Oral “Tablets, OralNCT00569036
Target IGF1R “Insulin-like growth factor I receptor inhibitor” CHEMBL575448
Target INSR “Insulin receptor inhibitor” CHEMBL575448