Drugs / PEPTIDE YY HUMAN (3-36)
last change Oct 2017 re-read 2 minutes ago

PEPTIDE YY HUMAN (3-36)

also known as PYY 3-36 · GT-001 · Peptide YY3-36

Peptide targets NPY2R via activation

Developed for
obesity disorder · eating disorder
Investigated by
University of Copenhagen · Aditech Pharma AB · Gila Therapeutics, Inc. · Hvidovre University Hospital · Nastech Pharmaceutical Company, Inc. · Pfizer
+1 more · University Hospital, Basel, Switzerland

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT02493959 May 2014 → Jul 2015 Hvidovre University Hospital Completed No outcome recorded
Phase 13 trials
Phase 1 NCT03490786 Jul → Aug 2017 eating disorder Gila Therapeutics, Inc. Completed No outcome recorded
Phase 1 NCT00468884 Oct 2006 → Feb 2007 University Hospital, Basel, Switzerland Completed No outcome recorded
Phase 1 NCT00331175 Jul → Dec 2006 obesity disorder Pfizer Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00537420 Oct 2007 → Jul 2008 obesity disorder Nastech Pharmaceutical Company, Inc. Completed No outcome recorded
Phase not applicable2 trials
NCT00940134 Mar 2011 → Jan 2012 obesity disorder University of Copenhagen Completed No outcome recorded
NCT00259233 Mar → May 2005 obesity disorder University of Copenhagen Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as PEPTIDE YY HUMAN (3-36) ChEMBL registry synonym — accepted as the source's own label CHEMBL4297971
Known as GT-001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03490786
Known as Peptide YY3-36 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00331175
Known as PYY 3-36 “12 obese subjects will receive peripheral administration of placebo and 4 escalating doses of PYY1-36 and another 12 obese subjects will receive peripheral administration of...” NCT00259233
5

“Our aim was to examine the effects of GLP-1 and PYY3-36, separately and in combination, on energy intake, energy expenditure, appetite sensations, glucose and fat metabolism,...” PMID 24735885 Apr 2014

“Biological: PYY 3-36NCT00940134

NCT00537420

NCT02493959

NCT00468884

Action Activate “Neuropeptide Y receptor type 2 agonist” CHEMBL4297971
Modality Peptide Peptide YY3-36” NCT00331175
Route Intravenous “administered by intravenous infusion” NCT00331175
Target NPY2R “Neuropeptide Y receptor type 2 agonist” CHEMBL4297971