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drugset / Trial / NCT02493959

Degradation of the Anorexic Hormone Peptide YY

NCT02493959 ↗

Phase 0 Completed 8 enrolled Hvidovre University Hospital University of Copenhagen · collab
NaSingle-groupSingle-blindBasic science

Summary

Peptide YY (PYY) is a gastrointestinal hormone released from the enteroendocrine cell upon food intake. The N-terminal truncated form, PYY3-36, exerts anorexic effects. In this study we want to investigate the kinetics of PYY1-36 and PYY3-36 and to examine whether a C-terminally degraded metabolite, PYY3-34, is formed after infusion of PYY.

Timeline

Start
2014-05
Primary completion
2015-07
Completion
2015-07

Drugs

EvaluationDrugModalityDoseRoute
Subject PEPTIDE YY HUMAN (3-36) Peptide 0.8 unknown Intravenous
Subject PYY1-36 Peptide 1.6 unknown Intravenous
Subject Sitagliptin Small molecule 100 mg —

Indications

No indication recorded.