Drugs / MK2461
last change Dec 2008 re-read 3 minutes ago

MK2461

Small molecule targets MET via inhibition

Developed for
cancer of unknown primary site · neoplasm
Investigated by
Merck Sharp & Dohme LLC

Trials 2

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00518739 Feb 2007 → Dec 2008 cancer of unknown primary site Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT00496353 Jun 2007 → Oct 2008 neoplasm Merck Sharp & Dohme LLC Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as MK2461 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00496353 ↗
1

NCT00518739 ↗

Action Inhibit “Hepatocyte growth factor receptor inhibitor” CHEMBL1822792 ↗
Modality Small molecule — CHEMBL1822792 ↗
Route Oral “Patients will be administered oral MK2461 twice daily” NCT00518739 ↗
Target MET “Hepatocyte growth factor receptor inhibitor” CHEMBL1822792 ↗