drugset / Trial / NCT00518739

MK2461 in Patients With Advanced Cancer (2461-001)(COMPLETED)

NCT00518739 ↗

Phase 1 Completed 25 enrolled Merck Sharp & Dohme LLC
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a first-in-human trial to establish the safety, tolerability, Recommended Phase II Dose (RP2D), pharmacodynamic, and clinical activity of MK2461.

Timeline

Start
2007-02
Primary completion
2008-12
Completion
2008-12

Drugs

EvaluationDrugModalityDoseRoute
Subject MK2461 Small molecule 60 mg Oral
Subject MK2461 Small molecule 240 mg Oral