Drugs / CEP-40783
last change Jun 2018 re-read 3 minutes ago

CEP-40783

also known as RXDX-106

Small molecule targets AXL, TYRO3 via inhibition

Investigated by
Hoffmann-La Roche

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 0 NCT03454243 Feb → Jun 2018 — Hoffmann-La Roche Terminated No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CEP-40783 ChEMBL registry synonym — accepted as the source's own label CHEMBL4650515 ↗
Known as RXDX-106 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03454243 ↗
Action Inhibit “TYRO3, AXL, and MER (TAM) Tyrosine Kinase Inhibitor” NCT03454243 ↗
Modality Small molecule “Oral Immunomodulatory TYRO3, AXL, and MER (TAM) Tyrosine Kinase Inhibitor” NCT03454243 ↗
Route Oral “continuous daily oral doses of RXDX-106” NCT03454243 ↗
Target AXL “TYRO3, AXL, and MER (TAM) Tyrosine Kinase Inhibitor” NCT03454243 ↗
Target TYRO3 “TYRO3, AXL, and MER (TAM) Tyrosine Kinase Inhibitor” NCT03454243 ↗