Drugs / Napabucasin

Trials 24 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 110 trials
Phase 1 NCT04299880 Feb 2020 → May 2021 Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1 NCT03525405 May → Jun 2018 Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1 NCT03411122 Jun 2017 → Jan 2018 Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1 NCT02641873 Dec 2015 → Dec 2016 colorectal cancer Sumitomo Pharma Co., Ltd. Completed No outcome recorded
Phase 1 NCT02467361 Aug 2015 → Jan 2021 cancer Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1 NCT02352558 May 2015 → Dec 2018 hematopoietic and lymphoid system neoplasm Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1 NCT02432326 Apr 2015 → Dec 2019 cancer Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1 NCT02358395 Feb 2015 → Nov 2017 hepatocellular carcinoma Sumitomo Pharma Co., Ltd. Completed No outcome recorded
Phase 1 NCT02231723 Aug 2014 → Jun 2020 pancreatic adenocarcinoma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1 NCT01775423 Mar 2009 → Aug 2015 cancer of unknown primary site Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1/26 trials
Phase 1/2 NCT02851004 Oct 2016 → Feb 2020 colorectal cancer Takayuki Yoshino Terminated No outcome recorded
Phase 1/2 NCT02315534 Mar 2015 → Oct 2018 glioblastoma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1/2 NCT02347917 Feb 2015 → May 2018 malignant pleural mesothelioma, non-small cell lung carcinoma Sumitomo Pharma Co., Ltd. Completed No outcome recorded
Phase 1/2 NCT02279719 Dec 2014 → Jul 2019 hepatocellular carcinoma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1/2 NCT02024607 Jan 2014 → Mar 2019 digestive system cancer Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1/2 NCT01325441 Apr 2011 → Jun 2021 cancer Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT03647839 Sep 2018 → Jan 2021 colorectal cancer Australasian Gastro-Intestinal Trials Group Completed No outcome recorded
Phase 2 NCT01776307 Mar 2012 → Jun 2018 colorectal cancer Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT03721744 Oct 2018 → Mar 2025 malignant pancreatic neoplasm 1Globe Health Institute LLC Unknown No outcome recorded
Phase 35 trials
Phase 3 NCT03522649 Apr 2018 → Nov 2021 1Globe Health Institute LLC Unknown No outcome recorded
Phase 3 NCT02993731 Dec 2016 → Mar 2020 pancreatic ductal adenocarcinoma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT02826161 Nov 2016 → Apr 2017 non-small cell lung carcinoma Sumitomo Pharma America, Inc. Terminated No outcome recorded
Phase 3 NCT02753127 Jun 2016 → Apr 2020 colorectal cancer Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT02178956 Oct 2014 → Sep 2017 gastric cancer, gastroesophageal junction adenocarcinoma Sumitomo Pharma America, Inc. Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT01830621 Comparator May 2013 → May 2016 colorectal carcinoma NCIC Clinical Trials Group Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 26 sources stand behind the page.

FieldValueCited text
Known as Napabucasin ClinicalTrials.gov intervention name — accepted as the source's own label NCT02993731
7

NCT02851004

NCT03522649

NCT03411122

NCT02753127

NCT04299880

NCT03525405

NCT02826161

Known as 2-acetylfuranonaphthoquinone ChEMBL registry synonym — accepted as the source's own label CHEMBL64130
Known as 2-acetylfuro-1,4-naphthoquinone ChEMBL registry synonym — accepted as the source's own label CHEMBL64130
Known as BBI608 “BBI-608 will be supplied free of charge by Boston Biomedical as capsules.” NCT03647839
15

NCT02352558

NCT02347917

NCT02231723

NCT02178956

NCT01775423

NCT02279719

NCT02641873

NCT01830621

NCT01325441

NCT02024607

NCT02315534

NCT02432326

NCT02358395

NCT02467361

NCT01776307

Known as GB201 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03721744
Known as Napabucasina ChEMBL registry synonym — accepted as the source's own label CHEMBL64130
Known as Napabucasine ChEMBL registry synonym — accepted as the source's own label CHEMBL64130
Action Inhibit “cancer stem cell pathway inhibitor napabucasin” NCT02753127
Modality Small molecule CHEMBL64130
Route Oral “Patients will receive BBI608 orally continuously at 200mg BID.” NCT01325441