drugset / Trial / NCT02178956

A Study of BBI608 Plus Weekly Paclitaxel to Treat Gastric and Gastro-Esophageal Junction Cancer

NCT02178956

Phase 3 Completed 714 enrolled Sumitomo Pharma America, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to find out whether it is better to receive a new drug, BBI608, in addition to paclitaxel chemotherapy or better to receive paclitaxel chemotherapy alone as second line treatment for gastric and gastroesophageal junction cancer after prior first line platinum and fluoropyrimidine based chemotherapy.

Timeline

Start
2014-10
Primary completion
2017-09-20
Completion
2017-09-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Napabucasin Small molecule 480 mg Oral
Background Paclitaxel Small molecule 80 mg/m2 Intravenous