Drugs / dipyrone
dipyrone
Trials 16 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT00841841 | Mar 2006 → Mar 2008 | — | University Center of Araraquara | Completed | No outcome recorded |
| Phase 34 trials | ||||||
| Phase 3 | NCT04972292 | Nov 2023 → May 2024 | — | Eurofarma Laboratorios S.A. | Completed | No outcome recorded |
| Phase 3 | NCT04641338 | Mar 2023 → Mar 2024 | neuropathy, painful | Brazilian Clinical Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT01147289 | Feb → Nov 2011 | sciatica | Eurofarma Laboratorios S.A. | Completed | No outcome recorded |
| Phase 3 | NCT02183220 | Oct 1998 → Jul 1999 | migraine disorder | Boehringer Ingelheim | Completed | No outcome recorded |
| Phase 46 trials | ||||||
| Phase 4 | NCT06950840 | Aug 2025 → May 2027 expected | chorioamnionitis | Wolfson Medical Center | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT05586373 | Oct 2022 → May 2023 | preeclampsia | Instituto Materno Infantil Prof. Fernando Figueira | Completed | No outcome recorded |
| Phase 4 | NCT03622489 | Mar 2017 → Aug 2018 | — | Wolfson Medical Center | Unknown | No outcome recorded |
| Phase 4 | NCT01359020 | Jan 2007 → Mar 2008 | — | Mantecorp Industria Quimica e Farmaceutica Ltd. | Completed | No outcome recorded |
| Phase 4 | NCT04595877 | Jan → May 2006 | — | Antonio Martín Duce | Completed | No outcome recorded |
| Phase 4 | NCT02184273 | Mar 2002 → Mar 2004 | — | Boehringer Ingelheim | Completed | No outcome recorded |
| Phase not applicable5 trials | ||||||
| — | NCT03389243 | Jan 2018 → Sep 2021 | — | Medical University of Silesia | Completed | No outcome recorded |
| — | NCT02973581 | Feb 2016 → Feb 2017 | — | Medical University of Silesia | Completed | No outcome recorded |
| — | NCT02971540 | Feb 2016 → Jul 2017 | lumbar disk disease | Medical University of Silesia | Completed | No outcome recorded |
| — | NCT00635037 | Jun 2004 → Feb 2005 | myofascial pain syndrome | Federal University of São Paulo | Completed | No outcome recorded |
| — | NCT00763997 | Feb → Dec 2004 | platelet aggregation, spontaneous | Ruhr University of Bochum | Completed | No outcome recorded |
Also used as a comparator or background therapy in 25 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 24 trials | ||||||
| Phase 2 | NCT05125978 Comparator | Sep 2026 → Jul 2028 | chronic pain syndrome | EMS | Withdrawn | No outcome recorded |
| Phase 2 | NCT04593329 Comparator | Mar → Aug 2023 | — | EMS | Withdrawn | No outcome recorded |
| Phase 2 | NCT01858402 Comparator | Dec 2009 → Mar 2011 | — | Baskent University | Completed | No outcome recorded |
| Phase 2 | NCT01008007 Comparator | Sep 2009 → May 2010 | — | Catalysis SL | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT02617199 Comparator | Nov 2015 → Dec 2016 | acute pancreatitis | Hospital General Naval de Alta Especialidad - Escuela Medico Naval | Unknown | No outcome recorded |
| Phase 37 trials | ||||||
| Phase 3 | NCT07626437 Comparator | May 2026 → Jun 2027 expected | nasal cavity disorder, viral respiratory tract infection | Brainfarma | Recruiting | No outcome recorded |
| Phase 3 | NCT06237231 Comparator | Feb → Mar 2025 overdue | — | EMS | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07666178 Comparator | Dec 2024 → Dec 2027 expected | — | Instituto do Coracao | Recruiting | No outcome recorded |
| Phase 3 | NCT02706015 Background | Oct 2020 → May 2021 | migraine disorder | Ache Laboratorios Farmaceuticos S.A. | Withdrawn | No outcome recorded |
| Phase 3 | NCT03255330 Comparator | Oct 2017 → Feb 2020 | spinal cord injury | Masaryk University | Withdrawn | No outcome recorded |
| Phase 3 | NCT03203070 Background | Mar → Sep 2017 | neuropathy, painful | Hospital General Universitario Elche | Unknown | No outcome recorded |
| Phase 3 | NCT02711241 Comparator | Jun → Dec 2010 | gastroenteritis | Hadassah Medical Organization | Terminated | No outcome recorded |
| Phase 45 trials | ||||||
| Phase 4 | NCT03244540 Background | Sep 2017 → Oct 2018 | neuropathy, painful | Medical University of Lublin | Completed | No outcome recorded |
| Phase 4 | NCT02804126 Background | Jun 2017 → Jul 2018 | neuropathy, painful | Michał Borys | Completed | No outcome recorded |
| Phase 4 | NCT02689024 Comparator | May 2016 → Jul 2023 | — | Academic Medical Center - University of Amsterdam | Terminated | No outcome recorded |
| Phase 4 | NCT04110587 Comparator | Dec 2013 → Jul 2019 | temporomandibular joint dysfunction syndrome | Universidad Complutense de Madrid | Completed | No outcome recorded |
| Phase 4 | NCT02239497 Background | Mar → Sep 2013 | — | Hospital Central Dr. Luis Ortega | Completed | No outcome recorded |
| Phase not applicable8 trials | ||||||
| — | NCT06390046 Background | Apr → Dec 2024 | — | Jagiellonian University | Completed | No outcome recorded |
| — | NCT07604376 Background | Mar 2024 → Jul 2026 overdue | — | Matild Keresztes | Recruiting | No outcome recorded |
| — | NCT05916716 Background | Aug 2022 → Dec 2023 | gingival recession | São Paulo State University | Unknown | No outcome recorded |
| — | NCT03594513 Background | Jul 2018 → Nov 2019 | gingival recession | São Paulo State University | Unknown | No outcome recorded |
| — | NCT02563587 Comparator | Sep 2015 → Jan 2016 | — | Hospital General Naval de Alta Especialidad - Escuela Medico Naval | Unknown | No outcome recorded |
| — | NCT02814279 Background | Feb 2014 → Oct 2015 | gingival recession | São Paulo State University | Completed | No outcome recorded |
| — | NCT01734954 Background | Apr → Aug 2013 | — | CES University | Unknown | No outcome recorded |
| — | NCT01263652 Comparator | Dec 2010 → Jun 2019 | — | Western Galilee Hospital-Nahariya | Withdrawn | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 41 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | dipyrone | “All patients will be submitted to the institution's standard management: multimodal analgesia with common analgesic (dipyrone 4 to 8 g / day or paracetamol 1500 to 2250 mg /...” NCT07666178 ↗26“Dexalgen® will be administered at a dose equivalent to dexamethasone 1.5 mg, dipyrone 500 mg, and hydroxocobalamin 5 mg (one ampoule for each type) a day at a single intramuscular dose” NCT01147289 ↗ “Intraoperative administration intravenous of dipyrone 30-50 mg/Kg and or intravenous ketoprofen 100 mg or diclofenac 75 mg or ketorolac 30 mg” NCT01734954 ↗ “Dipyrone pills, identical to the intervention (ibuprofen pills), will be administered every 6 hour for a maximum of five days” NCT05586373 ↗ “The dipyrone is a non-steroidal antiinflammatory which has an analgesic, antiinflammatory and antipyretic effect.” NCT02706015 ↗ “Both groups received intravenous analgesia with ketoprofen 100 mg regimen and dipyrone 1g c / 8 hs” NCT02239497 ↗ “intramuscular injection of one bulb of Dipyrone (600 mg)” NCT01008007 ↗ “10 mg/day cyclobenzaprine and 500 mg dipyrone every 8 h” NCT00635037 ↗ |
| Known as | Dipyrone: Novalgina | “Dipyrone: Novalgina” NCT00841841 ↗ |
| Known as | Metamizol | “Conventional treatment involves handling analgesic with non-steroidal anti-inflammatory drugs (paracetaol, metamizol and ketorolac) as prescribed by the doctor surgeon...” NCT02563587 ↗13“ketorolac 1mg/kg every 8 hours or metamizol 15 mg/kg every 8 hrs and intravenous opioids (buprenorphine 3 mcg / kg or tramadol 1mg/ kg in continuos infusion” NCT02617199 ↗ “Regular Tramadol, Metamizol, +/- Ibuprofen/Dexketorpofen/Parecoxib” NCT07604376 ↗ “coanalgesics in the form of Paracetamol, Dexac, and Metamizol” NCT06390046 ↗ “Metamizol 575 mg / 8h by mouth (Post-operatively)” NCT04110587 ↗ |
| Known as | Nolotil | “Dipyrone 2 g (Nolotil®, Europharma, Madrid, Spain); one ampoule in 50 mL of 0.9% saline solution as an intravenous infusion over 10 min.” NCT04595877 ↗ |
| Route | Intravenous | “Dipyrone is given in the operation room with 2,5 g intravenously” NCT00763997 ↗ |