Comparing Protocols for Analgesia Following Elective Cesarean Section

Phase 4 Unknown 120 enrolled Wolfson Medical Center

RandomizedParallel-groupOpen-labelTreatment

Summary

Women undergoing elective cesarian section will be assigned to 3 groups for postoperative analgesia: 1. Scheduled doses of IV acetaminophen + PO Ibuprofen 2. Scheduled doses of PO acetaminophen + PO Ibuprofen 3. "On demand" doses of acetaminophen, dipyrone and ibuprofen.

Timeline

Start: 2017-03-01
Primary completion: 2018-08-31
Completion: 2018-08-31

Publications

Dafna L, Herman HG, Ben-Zvi M, Bustan M, Sasson L, Bar J, Kovo M. Comparison of 3 protocols for analgesia control after cesarean delivery: a randomized controlled trial. Am J Obstet Gynecol MFM. 2019 May;1(2):112-118. doi: 10.1016/j.ajogmf.2019.04.002. Epub 2019 Apr 8.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Acetaminophen	Small molecule	1 g	Intravenous
Subject	Ibuprofen	Small molecule	400 mg	Oral
Background	Tramadol	Other / unclassified	100 mg	Intravenous
Subject	dipyrone	Unknown	1 g	Oral
Background	Morphine	Other / unclassified	5 mg	Intravenous
Background	Tramadol	Other / unclassified	100 mg	Intravenous

Indications

No indication recorded.