Drugs / 2-(1-HEXYLOXYETHYL)-2-DEVINYL PYROPHEOPHORBIDE-A

Trials 15

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 111 trials
Phase 1 NCT03757754 Jun 2015 → Jan 2019 esophageal cancer Zhejiang Hisun Pharmaceutical Co. Ltd. Unknown No outcome recorded
Phase 1 NCT01140178 Jun 2010 → Jan 2013 oral cavity carcinoma, oropharyngeal carcinoma Roswell Park Cancer Institute Completed No outcome recorded
Phase 1 NCT00670397 Jun 2010 → Nov 2011 head and neck cancer Roswell Park Cancer Institute Terminated No outcome recorded
Phase 1 NCT00675233 Apr 2008 → Jun 2013 head and neck cancer Roswell Park Cancer Institute Completed No outcome recorded
Phase 1 NCT01673074 Nov 2007 → Dec 2013 pleural cancer Abramson Cancer Center at Penn Medicine Completed No outcome recorded
Phase 1 NCT00470496 Oct 2006 → Oct 2011 adenoid cystic carcinoma, esthesioneuroblastoma, hypopharynx squamous cell carcinoma, inverted papilloma +13 Roswell Park Cancer Institute Completed No outcome recorded
Phase 1 NCT00526461 Feb 2004 → Jun 2013 lung cancer Roswell Park Cancer Institute Completed No outcome recorded
Phase 1 NCT01238042 Mar 2003 → Oct 2004 Barrett esophagus Roswell Park Cancer Institute Completed No outcome recorded
Phase 1 NCT00025571 Jun 2001 → Oct 2002 lung cancer Roswell Park Cancer Institute Completed No outcome recorded
Phase 1 NCT01236443 Aug 2000 → May 2003 Barrett esophagus, intraepithelial neoplasia Roswell Park Cancer Institute Completed No outcome recorded
Phase 24 trials
Phase 2 NCT03090412 Mar 2018 → Aug 2021 oral cavity squamous cell carcinoma Roswell Park Cancer Institute Terminated No outcome recorded Stop: Enrollment
Phase 2 NCT00528775 Aug 2007 → Nov 2009 lung cancer Roswell Park Cancer Institute Terminated No outcome recorded
Phase 2 NCT00281736 Feb 2004 → Jul 2007 esophageal cancer, precancerous condition Roswell Park Cancer Institute Completed No outcome recorded
Phase 2 NCT02119728 ? → Jan 2017 oropharynx squamous cell carcinoma, verrucous carcinoma of oral cavity Roswell Park Cancer Institute Withdrawn No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 16 sources stand behind the page.

FieldValueCited text
Known as 2-(1-hexyloxyethyl)-2 Devinyl Pyropheophorbide-a “A Phase I/II Study of Photodynamic Therapy (PDT) Using 2-[1-hexyloxyethyl]-2-devinylpyropheophorbide-a (HPPH) for the Treatment of High Grade Dysplasia, Carcinoma-in-situ and...” NCT01236443 ↗
6

“OBJECTIVES: To determine the safety of photodynamic therapy with 2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a (HPPH) in combination with surgery in patients with head and...” PMID 23868427 ↗ Jul 2013

“A Phase I Study Of Photodynamic Therapy (PDT) For The Treatment Of Basal Cell Carcinoma (BCC): A Drug/Light Dose Finding Study Utilizing 2-(1-HEXYLOXYETHYL)-2-DEVINYL...” NCT00017485 ↗

“Phase I Trial of Photodynamic Therapy With HPPH (2-1[Hexyloxyethyl]-2-devinylpyropheophorbide-a) for Treatment of Dysplasia, Carcinoma in Situ and Stage I Carcinoma of the Oral Cavity” NCT00670397 ↗

“Phase I Trial of Photodynamic Therapy With HPPH (2-1[Hexyloxyethyl]-2-devinylpyropheophorbide-a) for Treatment of Dysplasia, Carcinoma in Situ and T1 Carcinoma of the Larynx” NCT00675233 ↗

“A Phase I Study of Photodynamic Therapy (PDT) Using 2-(1-hexyloxyethyl)-2 Devinyl Pyropheophorbide-a (HPPH) for Treatment of Early Stage Lung Cancer - A Dose Ranging Study” NCT00025571 ↗

“photosensitizer (PS) 2-\[1-hexyloxyethyl\]-2-devinyl pyropheophorbide-a (HPPH) for injection” NCT03757754 ↗

Known as 2-[1-hydroxyethyl]-2-devinylpyropheophorbide-a “A Study to identify toxicity and optimal photodynamic treatment parameters using the photosensitizer 2-[1-hydroxyethyl]-2-devinylpyropheophorbide-a (HPPH) in high grade...” NCT01236443 ↗
Known as HPPH “Patients will be given HPPH, by intravenous injection prior to surgery.” NCT01673074 ↗
14

NCT00526461 ↗

NCT01140178 ↗

NCT01238042 ↗

NCT03090412 ↗

NCT00670397 ↗

NCT00470496 ↗

NCT01236443 ↗

NCT03757754 ↗

NCT00675233 ↗

NCT00017485 ↗

Show 4 more sources

Known as HPPH-PHOTOCLOR “A Phase I Study Of Photodynamic Therapy (PDT) For The Treatment Of Basal Cell Carcinoma (BCC): A Drug/Light Dose Finding Study Utilizing 2-(1-HEXYLOXYETHYL)-2-DEVINYL...” NCT00017485 ↗
Modality Other / unclassified “using the photosensitizer 2-[1-hydroxyethyl]-2-devinylpyropheophorbide-a (HPPH)” NCT01236443 ↗
Route Intravenous “Patients receive HPPH IV on day 1.” NCT00017485 ↗