drugset / Trial / NCT00670397

Photodynamic Therapy Using HPPH in Treating Patients With Recurrent Dysplasia, Carcinoma in Situ, or Stage I Oral Cavity Cancer

NCT00670397 ↗

Phase 1 Terminated 11 enrolled Roswell Park Cancer Institute
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Photodynamic therapy uses a drug, such as HPPH, that is absorbed by tumor cells. The drug becomes active when it is exposed to light. When the drug is active, tumor cells are killed. PURPOSE: This phase I trial is studying the side effects and best dose of photodynamic therapy using HPPH in treating patients with recurrent dysplasia, carcinoma in situ, or stage I oral cavity cancer.

Timeline

Start
2010-06
Primary completion
2011-11
Completion
2015-07

Outcome

Outcome not reported

Stopped: “safety issues”

Drugs

EvaluationDrugModalityDoseRoute
Subject 2-(1-HEXYLOXYETHYL)-2-DEVINYL PYROPHEOPHORBIDE-A Unknown — Intravenous

Indications