Drugs / Magnesium Isoglycyrrhizinate
last change Nov 2025 re-read 9 days ago

Magnesium Isoglycyrrhizinate

Developed for
drug-induced liver injury · chronic hepatitis B virus infection
Investigated by
Cttq · Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Trials 3

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT02734966 Dec 2007 → Dec 2008 drug-induced liver injury Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Completed No outcome recorded
Phase 42 trials
Phase 4 NCT03349008 Nov 2017 → Dec 2019 chronic hepatitis B virus infection Cttq Unknown No outcome recorded
Phase 4 NCT01802996 Mar 2013 → Aug 2014 drug-induced liver injury, neoplasm Cttq Unknown No outcome recorded
Comparator or background therapy3 trials
Phase 4 NCT07150624 Background Nov 2025 → Dec 2026 expected hepatocellular carcinoma Anhui Provincial Hospital Recruiting No outcome recorded
Phase 4 NCT04595916 Comparator Apr → Oct 2020 drug-induced liver injury Sichuan Haisco Pharmaceutical Group Co., Ltd Completed No outcome recorded
— NCT06922669 Background Jun 2025 → Mar 2027 expected drug-induced liver injury General Hospital of Shenyang Military Region Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-04-03 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Results 456例真实世界数据验证,天晴甘美把药物性肝损伤率降到3.5% cttq.com ↗
456例血液病患者使用异甘草酸镁(MgIG)预防保肝后,整体急性DILI发生率为3.5%,MgIG相关不良反应发生率低于3%,均处于较低水平[1]。

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as Magnesium Isoglycyrrhizinate “And 930mg of polyene phosphatidylcholine injection,twice a day, combined with 100mg of magnesium isoglycyrrhizinate injection once a day,from the 1st to the 5th day after the operation.” NCT07150624 ↗
5

NCT01802996 ↗

NCT03349008 ↗

NCT02734966 ↗

NCT04595916 ↗

NCT06922669 ↗

Known as 18.alpha.-glycyrrhizin magnesium ChEMBL registry synonym — accepted as the source's own label CHEMBL4297780 ↗
Route Intravenous “200mg IV on day 1-5” NCT01802996 ↗