Drugs / Acetohydroxamic Acid
Acetohydroxamic Acid
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | LITHOSTAT | — | 1983-05-31 | fda.gov ↗ |
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT03181828 | Mar 2017 → Jun 2018 | urea cycle disorder | Nicholas Ah Mew | Terminated | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT07393438 | Feb 2026 → Feb 2027 expected | multidrug-resistant tuberculosis, rifampicin-resistant tuberculosis | Shanghai Pulmonary Hospital, Shanghai, China | Not yet recruiting | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Acetohydroxamic Acid | ClinicalTrials.gov intervention name — accepted as the source's own label NCT07393438 ↗ |
| Known as | Acide acetohydroxamique | ChEMBL registry synonym — accepted as the source's own label CHEMBL734 ↗ |
| Known as | Acido acetohidroxamico | ChEMBL registry synonym — accepted as the source's own label CHEMBL734 ↗ |
| Known as | AHA | “The urease inhibitor, acetohydroxamic acid (AHA, Lithostat®, Mission Pharmacal), is an FDA-approved product for another indication- the treatment of struvite nephrolithiasis in...” NCT03181828 ↗1“acetohydroxamic acid (AHA) capsules combined with short-course regimens” NCT07393438 ↗ |
| Known as | Lithostat | ChEMBL registry synonym — accepted as the source's own label CHEMBL734 ↗ |
| Known as | NSC-176136 | ChEMBL registry synonym — accepted as the source's own label CHEMBL734 ↗ |
| Action | Inhibit | “The urease inhibitor, acetohydroxamic acid (AHA, Lithostat®, Mission Pharmacal), is an FDA-approved product” NCT03181828 ↗ |
| Modality | Small molecule | — CHEMBL734 ↗ |
| Route | Oral | “A single oral dose of 60 mg/kg acetohydroxamic acid rounded to the nearest 250 mg tablet.” NCT03181828 ↗ |