drugset / Trial / NCT03181828
Manipulating the Gut Microbiome Study
RandomizedCrossoverOpen-labelTreatment
Summary
The objective is to determine if acetohydroxamic acid (AHA) can prevent hydrolysis of urea by inhibiting the bacterial urease of gut flora of both healthy control adults as well as adults with urea cycle disorders
Timeline
- Start
- 2017-03-24
- Primary completion
- 2018-06-05
- Completion
- 2018-06-05
Outcome
Outcome not reported
Stopped: “The incidence of AEs was higher than the IB reported.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetohydroxamic Acid | Small molecule | 60 mg/kg | Oral |