Drugs / phenethyl isothiocyanate
last change Mar 2016 re-read 3 minutes ago

phenethyl isothiocyanate

Small molecule

Developed for
lung cancer · leukemia · lymphoproliferative syndrome
Investigated by
National Cancer Institute (NCI) · M.D. Anderson Cancer Center · NYU Langone Health · University of Minnesota

Trials 3

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT00968461 May 2013 → May 2015 leukemia, lymphoproliferative syndrome M.D. Anderson Cancer Center Withdrawn No outcome recorded
Phase 1 NCT00005883 ? → Apr 2001 lung cancer NYU Langone Health Completed No outcome recorded
Phase 21 trial · 1 met primary
Phase 2 NCT00691132 Feb 2009 → Jan 2013 lung cancer, nicotine dependence University of Minnesota Completed Met primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as phenethyl isothiocyanate ClinicalTrials.gov intervention name — accepted as the source's own label NCT00005883 ↗
2

NCT00968461 ↗

NCT00691132 ↗

Known as 2-Phenethyl isothiocyanate “2-Phenethyl isothiocyanate (PEITC), a natural product found as a conjugate in watercress and other cruciferous vegetables, is an inhibitor of the metabolic activation and lung...” PMID 26951845 ↗ Mar 2016
Known as PEITC “Phenethyl Isothiocyanate (PEITC)” NCT00968461 ↗
Action Inhibit “is an inhibitor of the metabolic activation and lung carcinogenicity of the tobacco carcinogen” PMID 26951845 ↗ Mar 2016
Modality Small molecule — CHEMBL151649 ↗
Route Oral “Patients receive phenethyl isothiocyanate orally 4 times a day for 30 days.” NCT00005883 ↗